Evidence map›Paper›PMID 31061062›Full record

Observational studyBMJ open2019

Prevalence and incidence of kidney diseases leading to hospital admission in people living with HIV in France: an observational nationwide study.

Magali Louis, Jonathan Cottenet, Arnaud Salmon-Rousseau, Mathieu Blot, Pierre-Henri Bonnot, Jean-Michel Rebibou, Pascal Chavanet, Christiane Mousson, Catherine Quantin, Lionel Piroth

Abstract readMulticenter StudyObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Magali LouisInfectious Diseases Department, University Hospital, Dijon, France.
Jonathan CottenetCHRU Dijon, Service de Biostatistique et d'Informatique Médicale (DIM), Université de Bourgogne, Dijon, France.
Arnaud Salmon-RousseauInfectious Diseases Department, University Hospital, Dijon, France.
Mathieu BlotInfectious Diseases Department, University Hospital, Dijon, France.
Pierre-Henri BonnotNephrology, University Hospital, Dijon, France.
Jean-Michel RebibouNephrology, University Hospital, Dijon, France.
Pascal ChavanetInfectious Diseases Department, University Hospital, Dijon, France.
Christiane MoussonNephrology, University Hospital, Dijon, France.
Catherine QuantinCHRU Dijon, Service de Biostatistique et d'Informatique Médicale (DIM), Université de Bourgogne, Dijon, France.
Lionel PirothInfectious Diseases Department, University Hospital, Dijon, France.ORCID 0000-0003-4478-1032

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo describe hospitalisations for kidney disease (KD) among people living with HIV (PLHIV) in France and to identify the factors associated with such hospitalisations since data on the epidemiology of KD leading to hospitalisation are globally scarce.

designObservational nationwide study using the French Programme de Médicalisation des Systèmes d'Information database.

settingFrance 2008-2013.

participantsAround 10 862 PLHIV out of a mean of 5 210 856 patients hospitalised each year. All hospital admissions with a main diagnosis code indicating KD (International Classification of Diseases, 10th revision codes, N00 to -N39) were collected.

main outcome measuresThe prevalence and incidence of KD leading to hospital admission in PLHIV and the associated risk factors.

resultsThe prevalence of patients hospitalised for KD was 1.5 higher in PLHIV than in the general population, and increased significantly from 3.0% in 2008 to 3.7% in 2013 (p<0.01). The main cause of hospitalisation for KD was acute renal failure (ARF, 25.4%). Glomerular diseases remained stable (6.4%) throughout the study period, focal segmental glomerulosclerosis being the main diagnosis (37.6%). Only 41.3% of patients hospitalised for glomerular disease were biopsied. The other common motives for admission were nephrolithiasis (22.1%) and pyelonephritis (22.6%).The 5-year cumulative incidence of KD requiring hospitalisation was 5.9% in HIV patients newly diagnosed for HIV in 2009. Factors associated with a higher risk of incident KD requiring hospitalisation were cardiovascular disease (HR 3.30, 95% CI 1.46 to 7.49), and, for female patients, AIDS (HR 2.45, 95% CI 1.07 to 5.58). Two-thirds of hospitalisations for incident ARF occurred in the first 2 years of follow-up.

conclusionsHospital admission for KD is more frequent in PLHIV than in the general population and increases over time. ARF remains the leading cause. Glomerular diseases are infrequently documented by renal biopsies. Older patients and those with cardiovascular disease are particularly concerned.

Indexed as

AdultAgedAged, 80 and overFemaleFranceHIV InfectionsHospitalizationHumansIncidenceKidney DiseasesMaleMiddle AgedPrevalenceRetrospective Studiesacute renal failureglomerular diseaseHIVhospitalisationkidney disease

Identifiers

PMID31061062
PMCPMC6501953

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