Evidence map›Paper›PMID 31061051›Full record

Observational studyBMJ open2019

Sexually transmitted infections in young people and factors associated with HIV coinfection: an observational study in a large city.

Alexis Sentís, Mario Martin-Sanchez, Maider Arando, Martí Vall, María Jesus Barbera, Inma Ocaña, Ana González Cordón, Mercè Alsina, Gemma Martin-Ezquerra, Hernando Knobel and 6 more

Abstract readObservational Study
In one paragraph

Observational study in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. High rates of Treponema pallidum, Neisseria gonorrhoeae, Chlamydia trachomatis, or Trichomonas vaginalis co-infection in people with HIV: a systematic review and meta-analysis.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Pooled it
  2. Pooled it
  3. Perceptions of adolescents regarding sexual and reproductive health role models.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Alexis SentísEpidemiology Service, Public Health Agency of Barcelona (ASPB), Barcelona, Spain.ORCID 0000-0002-8132-5645
Mario Martin-SanchezEpidemiology Service, Public Health Agency of Barcelona (ASPB), Barcelona, Spain.ORCID 0000-0002-2221-5331
Maider ArandoHospital de la Vall d'Hebron, Universitat Autònoma de Barcelona, Spain.
Martí VallHospital de la Vall d'Hebron, Universitat Autònoma de Barcelona, Spain.
María Jesus BarberaHospital de la Vall d'Hebron, Universitat Autònoma de Barcelona, Spain.
Inma OcañaHospital de la Vall d'Hebron, Universitat Autònoma de Barcelona, Spain.
Ana González CordónHospital Clínic de Barcelona, Universitat de Barcelona, Barcelona, Spain.
Mercè AlsinaHospital Clínic de Barcelona, Universitat de Barcelona, Barcelona, Spain.
Gemma Martin-EzquerraHospital del Mar, Universitat Autonòma de Barcelona, Barcelona, Spain.
Hernando KnobelHospital del Mar, Universitat Autonòma de Barcelona, Barcelona, Spain.
Mercè GurguíHospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain.
Alvaro VivesHospital Puigvert, Universitat Autònoma de Barcelona, Spain.
Josep CollHospital Tries i Pujol, Universitat Autònoma de Barcelona, Badalona, Barcelona, Spain.
Joan Artur CaylàEpidemiology Service, Public Health Agency of Barcelona (ASPB), Barcelona, Spain.
Patricia Garcia de OlallaEpidemiology Service, Public Health Agency of Barcelona (ASPB), Barcelona, Spain.
STI-HIV group of Barcelona

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesYoung people are a critical target group for sexually transmitted infections (STI) surveillance due to their particular behavioural and social related vulnerability. The aim of this study was to describe the epidemiological characteristics and trends in the incidence of gonorrhoea, syphilis, HIV and venereal lymphogranuloma (LGV) among 15-24-year-olds in Barcelona, and to determine factors associated with HIV coinfection.

designWe performed a population-based incidence study covering the 2007-2015 period.

participantsAll new cases of STI-HIV, gonorrhoea, infectious syphilis and LGV-notified to the epidemiological surveillance system in Barcelona between 2007 and 2015. 1218 cases were studied: 84.6% were men, 19.3% were 15-19 years old and 50.6% were born in Spain. Among men, 73.7% were men who have sex with men (MSM); among women, 85.6% were women that have sex with men. PRIMARY AND SECONDARY OUTCOMES: Incidence of HIV, gonorrhoea, infectious syphilis and LGV. HIV coinfection.

resultsThere was an increase in the incidence of gonorrhoea, from 1.9 cases per 10 000 people in 2007 to 7.6/10 000 in 2015 (p<0.01), in MSM from 27.1 to 228.8/10 000 (p<0.01). The incidence of syphilis increased from 0.4/10 000 in 2007 to 3.1/10 000 in 2015 (significant in men only, p<0.01), in MSM from 18.1 to 116.9/10 000 (p<0.01). The incidence of HIV showed a non-significant increase in men (p=0.27), and that of LGV remained stable (p=0.59). Factors associated with increased risk of HIV coinfection included being MSM (adjusted OR[ORa]=14.14, 95% CI 3.34 to 59.91) and having >10 sexual partners (ORa=4.11, 95% CI 1.53 to 11.01) or STI diagnosis during the previous 12 months (ORa=2.06; 95% CI 1.13 to 3.77).

conclusionsThe incidence of gonorrhoea and syphilis among 15-24-year-olds increased, while HIV infection remained stable but with a high incidence among MSM. Being MSM, having sex with multiple partners and having a diagnosis of an STI in the previous 12 months were factors associated with HIV coinfection.

Indexed as

AdolescentCoinfectionFemaleGonorrheaHIV InfectionsHomosexuality, MaleHumansIncidenceMaleSpainSyphilisUrban HealthYoung AdultadolescentsHiv coinfectionincidence studysexually transmitted infectionstrendsyoung people

Identifiers

PMID31061051
PMCPMC6502227

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.