Evidence map›Paper›PMID 31061020›Full record

ArticleBMJ open2019

Association between parity and persistent weight gain at age 40-60 years: a longitudinal prospective cohort study.

Gerbrand Albertus Zoet, Nina D Paauw, Katrien Groenhof, Arie Franx, Ron T Gansevoort, Henk Groen, Bas Van Rijn, Titia Lely

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
3.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 34 citations in OpenAlex.

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  8. Adverse pregnancy outcomes and risk of type 2 diabetes in postmenopausal women.American journal of obstetrics and gynecology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 5 countries.

Gerbrand Albertus ZoetObstetrics & Gynaecology, University Medical Center Utrecht, Utrecht, The Netherlands.
Nina D PaauwObstetrics & Gynaecology, University Medical Center Utrecht, Utrecht, The Netherlands.
Katrien GroenhofJulius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands.
Arie FranxObstetrics & Gynaecology, University Medical Center Utrecht, Utrecht, The Netherlands.
Ron T GansevoortDivision of Nephrology, University Medical Center Groningen, Groningen, The Netherlands.
Henk GroenDepartment of Epidemiology, University Medical Center Groningen, Groningen, The Netherlands.
Bas Van Rijn *Obstetrics & Gynaecology, University Medical Center Utrecht, Utrecht, The Netherlands.
Titia Lely *Obstetrics & Gynaecology, University Medical Center Utrecht, Utrecht, The Netherlands.
University Medical Center Utrecht · NLUniversity Medical Center Groningen · NLHealth and Human Development (2HD) Research Network · CMOklahoma State University Center for Health Sciences · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesPhysiological metabolic adaptations occur in the pregnant woman. These may persist postpartum and thereby contribute to an unfavourable cardiovascular disease (CVD) risk profile in parous women. The aim of the current study is to assess time-dependent changes of cardiometabolic health in parous women compared with nulliparous women. DESIGN AND

settingWe studied data of 2459 women who participated in the Prevention of Renal and Vascular End-stage Disease study, a population-based prospective longitudinal cohort for assessment of CVD and renal disease in the general population.

participantsWe selected women ≥40 years at the first visit, who reported no new pregnancies during the four follow-up visits. All women were categorised in parity groups, and stratified for age. OUTCOME MEASURES: We compared body mass index (BMI), high-density lipoprotein (HDL) cholesterol, blood pressure as continuous measurements and as clinical relevant CVD risk factors among parity groups over the course of 6 years using generalised estimating equation models adjusted for age.

resultsThe BMI was significantly higher in women para 2 or more in all age categories: per child, the BMI was 0.6 kg/m

conclusionsHigher parity is associated with higher BMI, lower HDL cholesterol and a higher prevalence of cardiovascular risk factors, which is constant over time. These findings warrant for prospective research assessing determinants of cardiometabolic health at earlier age to understand the role of pregnancy in the development of CVD in women.

Indexed as

ParityWeight GainAdultAge FactorsBlood PressureBody Mass IndexCardiovascular DiseasesCholesterol, HDLFemaleHumansLongitudinal StudiesMiddle AgedProspective StudiesRisk FactorsCholesterol, HDLBMIcardiovascular risk factorsHDL cholesterolhypertensionparitypregnancy

Identifiers

PMID31061020
PMCPMC6501996
OpenAlexW2942564895

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.