Evidence map›Paper›PMID 31060627›Full record

Trial reportJournal of cardiothoracic surgery2019

Differential lung ventilation for increased oxygenation during one lung ventilation for video assisted lung surgery.

Ran Kremer, Wisam Aboud, Ori Haberfeld, Maruan Armali, Michal Barak

2 registry-linked trialsOpen access · goldAbstract readComparative StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of cardiothoracic surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03563612 nacompletednot on this map

Differential Lung Ventilation vs. CPAP During One Lung Ventilation for Video Assisted Lung Surgery

TypeinterventionalSponsorRambam Health Care CampusRan2017 to 2017Enrolled29ConditionsOne Lung Ventilation, Continuous Positive Airway Pressure, Differential Lung VentilationArmscpap
NCT04926649 naunknown statusnot on this mapstarted 2021, after this paper: background citation

The High-frequency Low-volume Ventilation (HFLVV) for Hypoxemia During the Weaning From Cardiopulmonary Bypass in Robot-assisted Cardiac Surgery

TypeinterventionalSponsorDaping Hospital and the Research Institute of Surgery of the Third Military Medical UniversityRan2021 to 2022Enrolled56ConditionsHypoxemiaArmsDifferential ventilation to the non-dependent lung
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Ran KremerDepartment of Thoracic Surgery, Rambam Health Care Campus, Haifa, Israel.
Wisam AboudDepartment of Anesthesiology, the Baruch Padeh Medical Center, Poriya, Tiberius, Israel.
Ori HaberfeldDepartment of Thoracic Surgery, Rambam Health Care Campus, Haifa, Israel.
Maruan ArmaliDepartment of Anesthesiology, the Baruch Padeh Medical Center, Poriya, Tiberius, Israel.
Michal BarakDepartment of Anesthesiology, Rambam Health Care Campus and the Rappaport Faculty of Medicine, Technion - Israel Institute of Technology, POB 9602, 31096, Haifa, Israel. 10michal@gmail.com.
Rambam Health Care Campus · ILPoriya Medical Center · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOne lung ventilation (OLV) is the technique used during lung resection surgery in order to facilitate optimal surgical conditions. OLV may result in hypoxemia due to the shunt created. Several techniques are used to overcome the hypoxemia, one of which is continuous positive airway pressure (CPAP) to the non-dependent lung. Another technique is ventilating the non-dependent lung with a minimal volume, thus creating differential lung ventilation (DLV). In this study we compared the efficacy of CPAP to DLV during video assisted thoracoscopic lung resection. PATIENTS AND

methodThis is a prospective study of 30 adult patients undergoing elective video assisted thoracoscopic lung lobectomy. Each patient was ventilated in four modes: two lung ventilation, OLV, OLV + CPAP and OLV + DLV. Fifteen patients were ventilated with CPAP first and DLV next, and the other 15 were ventilated with DLV first and then CPAP. Five minutes separated each mode, during which the non-dependent lung was open to room air. We measured the patient's arterial blood gas during each mode of ventilation. The surgeons, who were blinded to the ventilation technique, were asked to assess the surgical conditions at each stage.

resultsOxygenation during OLV+ CPAP was significantly lower that OLV + DLV (p = 0.018). There were insignificant alterations of pH, PCO2 and HCO3 during the different ventilating modes. The surgeons' assessments of interference in the field exposure between OLV + CPAP or OLV + DLV was found to be insignificant (p = 0.073).

conclusionsDuring OLV, DLV is superior to CPAP in improving patient's oxygenation, and may be used where CPAP failed.

trial registrationClinicalTrials.gov NCT03563612 . Registered 9 June 2018, retrospectively (due to clerical error).

Indexed as

HypoxiaOne-Lung VentilationOxygenPulmonary Surgical ProceduresAgedBlood Gas AnalysisContinuous Positive Airway PressureCross-Over StudiesFemaleHumansMaleMiddle AgedPneumonectomyProspective StudiesSingle-Blind MethodThoracic Surgery, Video-AssistedOxygenContinuous positive airway pressureDifferential lung ventilationOne lung ventilation

Identifiers

PMID31060627
PMCPMC6503433
OpenAlexW2948016141

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.