ArticleImplementation science : IS2019
Barriers and facilitators to the successful development, implementation and evaluation of care bundles in acute care in hospital: a scoping review.
Article in Implementation science : IS, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- Is there a way to reduce the infection associated with external ventricular shunts? A systematic review and meta-analysis of the recent bundle of care.Neurosurgical review · 2026Pooled it
- What Is the Impact of Care Bundles on the Prevalence or Incidence of Pressure Ulcers Among At-Risk Adults in the Acute Care Setting? A Systematic Review.International wound journal · 2025Pooled it
- Effect of acute kidney injury care bundle on kidney outcomes in cardiac patients receiving critical care: a systematic review and meta-analysis.BMC nephrology · 2025Pooled it
- Quality of fluid balance charting and interventions to improve it: a systematic review.BMJ open quality · 2023Pooled it
- Barriers and Facilitators to Implementing Interventions for Reducing Avoidable Hospital Readmission: Systematic Review of Qualitative Studies.International journal of health policy and management · 2023Pooled it
- Perioperative care bundles for the prevention of surgical-site infections: meta-analysis.The British journal of surgery · 2022Pooled it
- Perioperative interventions for prevention of postoperative pulmonary complications: systematic review and meta-analysis.BMJ (Clinical research ed.) · 2020Pooled it
- Impact of a Visualization Training Platform on PICU Nurses' Pain Assessment Skill in Critically Ill Children: A Mixed-Methods Randomized Controlled Trial.Nursing open · 2026Trial
- OASI2: a cluster randomised hybrid evaluation of strategies for sustainable implementation of the Obstetric Anal Sphincter Injury Care Bundle in maternity units in Great Britain.Implementation science : IS · 2021Trial
- Use of Implementation Science in Enhanced Recovery After Surgery Protocols: A Scoping Review.World journal of surgery · 2026Article
- Implementation competence for evidence-based practice among vascular access specialist team nurses: a mixed-method study.BMC nursing · 2026Article
- Development of implementation strategies for the National Emergency Airway Registry for Pediatric Emergency Medicine (NEAR4PEM) pre-intubation checklist: a prospective, pre-implementation planning study.Implementation science communications · 2026Article
- Article
- Barriers to implementing a pharmacist-led COPD CARE bundle in rural settings: a qualitative evaluation.BMJ open respiratory research · 2026Article
- Creation of an Implementation Blueprint for the National Emergency Airway Registry for Pediatric Emergency Medicine (NEAR4PEM) Pre-Intubation Checklist.Research square · 2026Article
- Designing complex health system interventions: an integrated theory-informed approach.Frontiers in health services · 2026Review
- Barriers and enablers to the implementation of a perinatal care bundle: the Perinatal Excellence to Reduce Injury in Premature Birth project.Frontiers in pediatrics · 2026Article
- Practitioners' perspectives on implementation of acute virtual wards: A scoping review.PLOS digital health · 2025Article
- Variable use of modern abdominal wall closure techniques at emergency laparotomy - an international, cross-sectional survey of surgical practice.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025Article
- Safety and efficacy of prophylactic onlay resorbable synthetic mesh with a comprehensive wound bundle at laparotomy closure in high-risk emergency abdominal surgery: an observational study.World journal of emergency surgery : WJES · 2025Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
backgroundCare bundles are small sets of evidence-based recommendations, designed to support the implementation of evidence-based best clinical practice. However, there is variation in the design and implementation of care bundles, which may impact on the fidelity of delivery and subsequently their clinical effectiveness.
methodsA scoping review was carried out using the Arksey and O'Malley framework to identify the literature reporting on the design, implementation and evaluation of care bundles. The Embase, CINAHL, Cochrane and Ovid MEDLINE databases were searched for manuscripts published between 2001 and November 2017; hand-searching of references and citations was also undertaken. Data were initially assessed using a quality assessment tool, the Downs and Black checklist, prior to further analysis and narrative synthesis. Implementation strategies were classified using the Expert Recommendations for Implementing Change (ERIC) criteria.
resultsTwenty-eight thousand six hundred ninety-two publications were screened and 348 articles retrieved in full text. Ninety-nine peer-reviewed quantitative publications were included for data extraction. These consisted of one randomised crossover trial, one randomised cluster trial, one case-control study, 20 prospective cohort studies and 76 non-parallel cohort studies. Twenty-three percent of studies were classified as poor based on Downs and Black checklist, and reporting of implementation strategies lacked structure. Negative associations were found between the number of elements in a bundle and compliance (Spearman's rho = - 0.47, non-parallel cohort and - 0.65, prospective cohort studies), and between the complexity of elements and compliance (p < 0.001, chi-squared = 23.05). Implementation strategies associated with improved compliance included evaluative and iterative approaches, development of stakeholder relationships and education and training strategies.
conclusionCare bundles with a small number of simple elements have better compliance rates. Standardised reporting of implementation strategies may help to implement care bundles into clinical practice with high fidelity.
trial registrationThis review was registered on the PROSPERO database: CRD 42015029963 in December 2015.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.