Evidence map›Paper›PMID 31060358›Full record

ArticleJournal of the American Chemical Society2019

Characterization of the Preprocessed Copper Site Equilibrium in Amine Oxidase and Assignment of the Reactive Copper Site in Topaquinone Biogenesis.

Charles N Adelson, Esther M Johnston, Kimberly M Hilmer, Hope Watts, Somdatta Ghosh Dey, Doreen E Brown, Joan B Broderick, Eric M Shepard, David M Dooley, Edward I Solomon

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the American Chemical Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Insight into the Spatial Arrangement of the Lysine Tyrosylquinone and CuInternational journal of molecular sciences · 2022
    Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Charles N AdelsonDepartment of Chemistry , Stanford University , Stanford , California 94305 , United States.
Esther M JohnstonDepartment of Chemistry , Stanford University , Stanford , California 94305 , United States.ORCID 0000-0001-7807-4729
Kimberly M HilmerDepartment of Chemistry and Biochemistry , Montana State University , Bozeman , Montana 59717 , United States.
Hope WattsDepartment of Chemistry and Biochemistry , Montana State University , Bozeman , Montana 59717 , United States.
Somdatta Ghosh DeyDepartment of Chemistry , Stanford University , Stanford , California 94305 , United States.ORCID 0000-0002-6142-2202
Doreen E BrownDepartment of Chemistry and Biochemistry , Montana State University , Bozeman , Montana 59717 , United States.
Joan B BroderickDepartment of Chemistry and Biochemistry , Montana State University , Bozeman , Montana 59717 , United States.ORCID 0000-0001-7057-9124
Eric M ShepardDepartment of Chemistry and Biochemistry , Montana State University , Bozeman , Montana 59717 , United States.
David M DooleyDepartment of Chemistry and Biochemistry , Montana State University , Bozeman , Montana 59717 , United States.
Edward I SolomonDepartment of Chemistry , Stanford University , Stanford , California 94305 , United States.ORCID 0000-0003-0291-3199
Montana State University · USStanford University · USUniversity of Rhode Island · US

Funding

Structure/Function Correlations Over Copper EnzymesR01DK031450 · NIDDK · STANFORD UNIVERSITY · PI EDWARD I SOLOMON · 1986 to 2026
$8.7M
SPECTROSCOPIC STUDIES OF COPPER CLUSTERS IN PROTEINSR37DK031450 · NIDDK · STANFORD UNIVERSITY · PI SOLOMON, EDWARD I · 1994 to 2011
$5.7M
NIDDK NIH HHS R01 DK031450NIDDK NIH HHS R37 DK031450
6 · The paper itself

Abstract

Copper-dependent amine oxidases produce their redox active cofactor, 2,4,5-trihydroxyphenylalanine quinone (TPQ), via the Cu

Indexed as

Amine Oxidase (Copper-Containing)Binding SitesCatalytic DomainCopperDihydroxyphenylalanineModels, Molecular6-hydroxydopa quinoneAmine Oxidase (Copper-Containing)CopperDihydroxyphenylalanine

Identifiers

PMID31060358
PMCPMC6568004
OpenAlexW2944753406

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.