Evidence map›Paper›PMID 31060222›Full record

ReviewAntibiotics (Basel, Switzerland)2019

Intracellular Penetration and Effects of Antibiotics on

Suzanne Bongers, Pien Hellebrekers, Luke P H Leenen, Leo Koenderman, Falco Hietbrink

Open access · goldAbstract readReview
In one paragraph

Review in Antibiotics (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 94 citations in OpenAlex.

  1. Article
  2. A zoonoticInfection and immunity · 2026
    Article
  3. Strain-specific persistence ofJournal of medical microbiology · 2026
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Staphylococcus aureus vertebral osteomyelitis: a single-centre retrospective cohort study with focus on oral flucloxacillin follow-up.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Article
  10. First Detection ofAnimals : an open access journal from MDPI · 2025
    Article
  11. Article
  12. Potassium-Doped MnOACS nano · 2025
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. mBio · 2024
    Article
  18. Circulating neutrophil anti-pathogen dysfunction in cirrhosis.JHEP reports : innovation in hepatology · 2023
    Review
  19. Article
  20. SK-03-92 Drug Kills IntracellularAntibiotics (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Suzanne BongersDepartment of Surgery, University Medical Center Utrecht, 3508 GA Utrecht, The Netherlands. shbongers@gmail.com.ORCID 0000-0001-5351-0934
Pien HellebrekersDepartment of Surgery, University Medical Center Utrecht, 3508 GA Utrecht, The Netherlands. hellebrekers.p@gmail.com.ORCID 0000-0002-3671-8415
Luke P H LeenenDepartment of Surgery, University Medical Center Utrecht, 3508 GA Utrecht, The Netherlands. l.p.h.leenen@umcutrecht.nl.
Leo KoendermanLaboratory of Translational Immunology, University Medical Center Utrecht, 3508 GA Utrecht, The Netherlands. l.Koenderman@umcutrecht.nl.ORCID 0000-0002-5636-6453
Falco HietbrinkDepartment of Surgery, University Medical Center Utrecht, 3508 GA Utrecht, The Netherlands. f.hietbrink@umcutrecht.nl.
University Medical Center Utrecht · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neutrophils are important assets in defense against invading bacteria like staphylococci. However, (dysfunctioning) neutrophils can also serve as reservoir for pathogens that are able to survive inside the cellular environment.

Indexed as

intracellular antibioticsintracellular pathogenneutrophilspolymorphonuclear leucocyte (PMN)Staphylococcus aureus

Identifiers

PMID31060222
PMCPMC6628357
OpenAlexW2942953505

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.