Evidence map›Paper›PMID 31059632›Full record

ArticleWorld psychiatry : official journal of the World Psychiatric Association (WPA)2019

Nonsocial and social cognition in schizophrenia: current evidence and future directions.

Michael F Green, William P Horan, Junghee Lee

4 registry-linked trialsOpen access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in World psychiatry : official journal of the World Psychiatric Association (WPA), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 304 papers, 12 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
304citing papers in PubMed, 12 pooled it
45.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04273685 naunknown statusnot on this map

Cognitive Remediation and Social Recovery in Early Psychosis

TypeinterventionalSponsorNational University of Ireland, Galway, IrelandRan2019 to 2022Enrolled40ConditionsPsychosisArmsCognitive remediation training, social recovery therapy, treatment as usual
NCT05105542 phase1completednot on this mapstarted 2021, after this paper: background citation

Muscarinic M1 Receptor Availability and Cognition in Schizophrenia

TypeinterventionalSponsorYale UniversityRan2021 to 2023Enrolled18ConditionsSchizophrenia, Schizoaffective Disorder, HealthyArms11C-EMO - A Novel PET Radiotracer for Muscarinic M1 Receptor, PET Scan
NCT05130853 nacompletednot on this mapstarted 2021, after this paper: background citation

Social Cognition Individualized Activities Lab (SoCIAL) for the Training of Social Cognition and Narrative Enhancement in Patients With Schizophrenia: A Randomized Controlled Study to Assess Efficacy and Generalization to Real-life Functioning

TypeinterventionalSponsorUniversity of Campania Luigi VanvitelliRan2021 to 2022Enrolled48ConditionsSchizophrenia, Schizo Affective DisorderArmsSocial Skills and Neurocognitive Individualized Training (SoCIAL), Treatmment-as-usual
NCT06978803 recruitingnot on this mapstarted 2024, after this paper: background citation

HYEEG Discourse in Psychosis: A Neurobehavioural Study

TypeobservationalSponsorDouglas Mental Health University InstituteRan2024 to 2026Enrolled110ConditionsPsychosis, Schizophrenia Disorders
3 · Its place in the literature

Who cites it

304 citing papers in PubMed, 12 syntheses or guidelines pooled it, 586 citations in OpenAlex.

  1. Pooled it
  2. The Australian and New Zealand journal of psychiatry · 2026
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  12. European Psychiatric Association guidance on assessment of cognitive impairment in schizophrenia.European psychiatry : the journal of the Association of European Psychiatrists · 2022
    Pooled it
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244 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Michael F GreenSemel Institute for Neuroscience and Human Behavior, Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles (UCLA), Los Angeles, CA, USA.
William P HoranSemel Institute for Neuroscience and Human Behavior, Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles (UCLA), Los Angeles, CA, USA.
Junghee LeeSemel Institute for Neuroscience and Human Behavior, Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles (UCLA), Los Angeles, CA, USA.
VA Greater Los Angeles Healthcare System · USUniversity of California, Los Angeles · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cognitive impairment in schizophrenia involves a broad array of nonsocial and social cognitive domains. It is a core feature of the illness, and one with substantial implications for treatment and prognosis. Our understanding of the causes, consequences and interventions for cognitive impairment in schizophrenia has grown substantially in recent years. Here we review a range of topics, including: a) the types of nonsocial cognitive, social cognitive, and perceptual deficits in schizophrenia; b) how deficits in schizophrenia are similar or different from those in other disorders; c) cognitive impairments in the prodromal period and over the lifespan in schizophrenia; d) neuroimaging of the neural substrates of nonsocial and social cognition, and e) relationships of nonsocial and social cognition to functional outcome. The paper also reviews the considerable efforts that have been directed to improve cognitive impairments in schizophrenia through novel psychopharmacology, cognitive remediation, social cognitive training, and alternative approaches. In the final section, we consider areas that are emerging and have the potential to provide future insights, including the interface of motivation and cognition, the influence of childhood adversity, metacognition, the role of neuroinflammation, computational modelling, the application of remote digital technology, and novel methods to evaluate brain network organization. The study of cognitive impairment has provided a way to approach, examine and comprehend a wide range of features of schizophrenia, and it may ultimately affect how we define and diagnose this complex disorder.

Indexed as

brain network organizationchildhood adversitycognitioncognitive enhancementcognitive neurosciencecognitive remediationcomputational modellingfunctional outcomemetacognitionSchizophreniasocial cognitionsocial neuroscience

Identifiers

PMID31059632
PMCPMC6502429
OpenAlexW2944611832

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.