ArticlePloS one2019
Child development in the context of biological and psychosocial hazards among poor families in Bangladesh.
Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.
- The Relationship between Social Environmental Factors and Motor Performance in 3- to 12-Year-Old Typically Developing Children: A Systematic Review.International journal of environmental research and public health · 2021Pooled it
- Four-year follow-up to a home-visiting intervention to promote early childhood development and prevent family violence in rural Rwanda: the Sugira Muryango cluster randomised trial.BMJ global health · 2025Trial
- Sexually Dimorphic Developmental Trajectories of Cortical and Subcortical Subfields in Early Childhood.International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience · 2026Article
- Haematological Inflammatory Indices in Preschoolers With Developmental Language Disorder: The Role of the Systemic Inflammation Response Index.International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience · 2026Article
- Breast milk cytokines and infant growth trajectories in a low-income community in Bangladesh.Pediatric research · 2026Article
- Altitude of area of residence as a risk factor for stunting in children aged 0-60 months: A systematic review and meta-analysis.Dialogues in health · 2026Review
- Bahir Dar Child Development Cross-Sectional Study, Ethiopia: study protocol.BMJ paediatrics open · 2025Article
- Examining the relationship between psychosocial adversity and inhibitory control: A functional magnetic resonance imaging study of children growing up in extreme poverty.Journal of experimental child psychology · 2025Article
- Exploration of auditory statistical learning, socioeconomic status, and language outcomes in Bangladeshi children: A functional near-infrared spectroscopy study.Developmental psychology · 2024Article
- Brain morphometry and chronic inflammation in Bangladeshi children growing up in extreme poverty.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Associations between the human immune system and gut microbiome with neurodevelopment in the first 5 years of life: A systematic scoping review.Developmental psychobiology · 2023Article
- Shining a light on cultural neuroscience: Recommendations on the use of fNIRS to study how sociocultural contexts shape the brain.Cultural diversity & ethnic minority psychology · 2023Review
- The Brain Imaging for Global Health (BRIGHT) Project: Longitudinal cohort study protocol.Gates open research · 2023Article
- Do Leadership, Organizational Communication, and Work Environment Impact Employees' Psychosocial Hazards in the Oil and Gas Industry?International journal of environmental research and public health · 2022Article
- Systemic inflammation during the first year of life is associated with brain functional connectivity and future cognitive outcomes.Developmental cognitive neuroscience · 2022Article
- Brain morphometry and diminished physical growth in Bangladeshi children growing up in extreme poverty: A longitudinal study.Developmental cognitive neuroscience · 2021Article
- Parenteral artemisinins are associated with reduced mortality and neurologic deficits and improved long-term behavioral outcomes in children with severe malaria.BMC medicine · 2021Observational
- Adaptation and Integration of Psychosocial Stimulation, Maternal Mental Health and Nutritional Interventions for Pregnant and Lactating Women in Rural Bangladesh.International journal of environmental research and public health · 2020Article
- Relating anthropometric indicators to brain structure in 2-month-old Bangladeshi infants growing up in poverty: A pilot study.NeuroImage · 2020Article
- Association of Genetic Risks With Autism Spectrum Disorder and Early Neurodevelopmental Delays Among Children Without Intellectual Disability.JAMA network open · 2020Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
It is well established that low resource environments early in life can predispose children to adverse health and compromised developmental outcomes. We explore possible mechanistic pathways underlying poor developmental outcomes in children growing up in a low resource setting in urban Bangladesh. We tested associations between psychosocial risks, namely maternal distress and poor caregiving experiences, and biological risks, namely poor growth (HAZ) and inflammation (C-reactive protein: CRP), and children's developmental outcomes. Child development was measured using the Mullen Scales of Early Learning (MSEL) at 6 and 27 months in one cohort, and using the MSEL and Wechsler Preschool and Primary Scale of Intelligence (WPPSI) at 36 and 60 months respectively in another cohort. In the younger cohort, we found that more inflammation (estimated by the child's CRP level at four months) predicted lower receptive language scores at 6 months, while more frequent caregiving interactions predicted higher receptive language scores at 6 months. In the older cohort, we found that at 27 months, a child's growth measured by his or her current HAZ was positively associated with gross motor, visual reception, receptive language, and expressive language scores. In the oldest cohort, we found that higher HAZ and more frequent stimulating activities in the home predicted higher motor and language scores, whereas more inflammation (as estimated by CRP over the first two years of life) predicted lower motor scores at 36 months. At 60 months, we found that HAZ and caregiving experiences were positively associated with verbal IQ, whereas inflammation was negatively associated with verbal IQ. This work identifies malnutrition, inflammation, and caregiving as potential sites of intervention to improve neurodevelopment in children growing up in global poverty.
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Registered trials
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