Evidence map›Paper›PMID 31059394›Full record

ReviewRadiographics : a review publication of the Radiological Society of North America, Inc

Photon-counting Detector CT: System Design and Clinical Applications of an Emerging Technology.

Shuai Leng, Michael Bruesewitz, Shengzhen Tao, Kishore Rajendran, Ahmed F Halaweish, Norbert G Campeau, Joel G Fletcher, Cynthia H McCollough

Abstract readComparative StudyReview
In one paragraph

Review in Radiographics : a review publication of the Radiological Society of North America, Inc. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 253 papers.

0numbers the graph read from it
0cells of the map it votes in
253citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

253 citing papers in PubMed.

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  3. Photon-counting detector computed tomography for temporal bone: does higher resolution matter?Current opinion in otolaryngology & head and neck surgery · 2026
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193 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shuai LengFrom the Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905 (S.L., M.B., S.T., K.R., N.G.C., J.G.F., C.H.M.); and Siemens Healthcare, Malvern, Pa (A.F.H.).ORCID http://orcid.org/0000-0002-6453-9481
Michael BruesewitzFrom the Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905 (S.L., M.B., S.T., K.R., N.G.C., J.G.F., C.H.M.); and Siemens Healthcare, Malvern, Pa (A.F.H.).
Shengzhen TaoFrom the Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905 (S.L., M.B., S.T., K.R., N.G.C., J.G.F., C.H.M.); and Siemens Healthcare, Malvern, Pa (A.F.H.).
Kishore RajendranFrom the Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905 (S.L., M.B., S.T., K.R., N.G.C., J.G.F., C.H.M.); and Siemens Healthcare, Malvern, Pa (A.F.H.).
Ahmed F HalaweishFrom the Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905 (S.L., M.B., S.T., K.R., N.G.C., J.G.F., C.H.M.); and Siemens Healthcare, Malvern, Pa (A.F.H.).
Norbert G CampeauFrom the Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905 (S.L., M.B., S.T., K.R., N.G.C., J.G.F., C.H.M.); and Siemens Healthcare, Malvern, Pa (A.F.H.).
Joel G FletcherFrom the Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905 (S.L., M.B., S.T., K.R., N.G.C., J.G.F., C.H.M.); and Siemens Healthcare, Malvern, Pa (A.F.H.).ORCID http://orcid.org/0000-0002-8941-5434
Cynthia H McColloughFrom the Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905 (S.L., M.B., S.T., K.R., N.G.C., J.G.F., C.H.M.); and Siemens Healthcare, Malvern, Pa (A.F.H.).ORCID http://orcid.org/0000-0002-5346-332X

Funding

Photon-Counting Spectral CT to Reduce Dose and Detect Early Vascular DiseaseR01EB016966 · NIBIB · MAYO CLINIC ROCHESTER · PI MCCOLLOUGH, CYNTHIA H · 2013 to 2017
$5.1M
EXTRAMURAL RES FACIL IMPROVEMENT PROG: POLYCYSTIC KIDNEY DISEASE, RENAL STUDIES,C06RR018898 · NCRR · MAYO CLINIC · PI BURNETT, JOHN C · 2004 to 2004
$2.3M
NCRR NIH HHS C06 RR018898NIBIB NIH HHS R01 EB016966
6 · The paper itself

Abstract

Photon-counting detector (PCD) CT is an emerging technology that has shown tremendous progress in the last decade. Various types of PCD CT systems have been developed to investigate the benefits of this technology, which include reduced electronic noise, increased contrast-to-noise ratio with iodinated contrast material and radiation dose efficiency, reduced beam-hardening and metal artifacts, extremely high spatial resolution (33 line pairs per centimeter), simultaneous multienergy data acquisition, and the ability to image with and differentiate among multiple CT contrast agents. PCD technology is described and compared with conventional CT detector technology. With the use of a whole-body research PCD CT system as an example, PCD technology and its use for in vivo high-spatial-resolution multienergy CT imaging is discussed. The potential clinical applications, diagnostic benefits, and challenges associated with this technology are then discussed, and examples with phantom, animal, and patient studies are provided.

Indexed as

PhotonsAnimalsContrast MediaEquipment DesignHumansIodine CompoundsRadiation DosageSignal-To-Noise RatioTomography, X-Ray ComputedContrast MediaIodine Compounds

Identifiers

PMID31059394
PMCPMC6542627

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.