Evidence map›Paper›PMID 31059393›Full record

ReviewRadiographics : a review publication of the Radiological Society of North America, Inc

Role of US LI-RADS in the LI-RADS Algorithm.

Shuchi K Rodgers, David T Fetzer, Helena Gabriel, James H Seow, Hailey H Choi, Katherine E Maturen, Ashish P Wasnik, Tara A Morgan, Nirvikar Dahiya, Mary K O'Boyle and 3 more

Abstract readReview
In one paragraph

Review in Radiographics : a review publication of the Radiological Society of North America, Inc. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Prevention, surveillance, and early detection of hepatocellular carcinoma - a Brazilian multidisciplinary consensus.Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2026
    Guideline
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Optimizing US for HCC surveillance.Abdominal radiology (New York) · 2025
    Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Hepatocellular Carcinoma from a Hepatologist's Perspective.Seminars in interventional radiology · 2023
    Review
  12. Article
  13. Review
  14. Review
  15. Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Shuchi K RodgersFrom the Department of Radiology, Einstein Medical Center, 5501 Old York Rd, Levy Ground, Philadelphia, PA 19141 (S.K.R.); Department of Radiology, University of Texas Southwestern Medical Center, Dallas, Tex (D.T.F.); Department of Radiology, Northwestern Memorial Hospital, Chicago, Ill (H.G.); Department of Radiology, Royal Perth Hospital, Perth, Australia (J.H.S.); Department of Radiology, Stanford University School of Medicine, Stanford, Calif (H.H.C.); Department of Radiology, University of Michigan Health System, Ann Arbor, Mich (K.E.M., A.P.W.); Department of Radiology and Biomedical Imaging, University of California-San Francisco, San Francisco, Calif (T.A.M.); Department of Radiology, Mayo Clinic, Phoenix, Ariz (N.D.); Department of Radiology (M.K.O., Y.K.) and Liver Imaging Group, Department of Radiology (C.B.S.), University of California-San Diego Medical Center, San Diego, Calif; and Department of Radiology, Stanford University Medical Center, Stanford, Calif (A.K.).
David T FetzerFrom the Department of Radiology, Einstein Medical Center, 5501 Old York Rd, Levy Ground, Philadelphia, PA 19141 (S.K.R.); Department of Radiology, University of Texas Southwestern Medical Center, Dallas, Tex (D.T.F.); Department of Radiology, Northwestern Memorial Hospital, Chicago, Ill (H.G.); Department of Radiology, Royal Perth Hospital, Perth, Australia (J.H.S.); Department of Radiology, Stanford University School of Medicine, Stanford, Calif (H.H.C.); Department of Radiology, University of Michigan Health System, Ann Arbor, Mich (K.E.M., A.P.W.); Department of Radiology and Biomedical Imaging, University of California-San Francisco, San Francisco, Calif (T.A.M.); Department of Radiology, Mayo Clinic, Phoenix, Ariz (N.D.); Department of Radiology (M.K.O., Y.K.) and Liver Imaging Group, Department of Radiology (C.B.S.), University of California-San Diego Medical Center, San Diego, Calif; and Department of Radiology, Stanford University Medical Center, Stanford, Calif (A.K.).
Helena GabrielFrom the Department of Radiology, Einstein Medical Center, 5501 Old York Rd, Levy Ground, Philadelphia, PA 19141 (S.K.R.); Department of Radiology, University of Texas Southwestern Medical Center, Dallas, Tex (D.T.F.); Department of Radiology, Northwestern Memorial Hospital, Chicago, Ill (H.G.); Department of Radiology, Royal Perth Hospital, Perth, Australia (J.H.S.); Department of Radiology, Stanford University School of Medicine, Stanford, Calif (H.H.C.); Department of Radiology, University of Michigan Health System, Ann Arbor, Mich (K.E.M., A.P.W.); Department of Radiology and Biomedical Imaging, University of California-San Francisco, San Francisco, Calif (T.A.M.); Department of Radiology, Mayo Clinic, Phoenix, Ariz (N.D.); Department of Radiology (M.K.O., Y.K.) and Liver Imaging Group, Department of Radiology (C.B.S.), University of California-San Diego Medical Center, San Diego, Calif; and Department of Radiology, Stanford University Medical Center, Stanford, Calif (A.K.).
James H SeowFrom the Department of Radiology, Einstein Medical Center, 5501 Old York Rd, Levy Ground, Philadelphia, PA 19141 (S.K.R.); Department of Radiology, University of Texas Southwestern Medical Center, Dallas, Tex (D.T.F.); Department of Radiology, Northwestern Memorial Hospital, Chicago, Ill (H.G.); Department of Radiology, Royal Perth Hospital, Perth, Australia (J.H.S.); Department of Radiology, Stanford University School of Medicine, Stanford, Calif (H.H.C.); Department of Radiology, University of Michigan Health System, Ann Arbor, Mich (K.E.M., A.P.W.); Department of Radiology and Biomedical Imaging, University of California-San Francisco, San Francisco, Calif (T.A.M.); Department of Radiology, Mayo Clinic, Phoenix, Ariz (N.D.); Department of Radiology (M.K.O., Y.K.) and Liver Imaging Group, Department of Radiology (C.B.S.), University of California-San Diego Medical Center, San Diego, Calif; and Department of Radiology, Stanford University Medical Center, Stanford, Calif (A.K.).
Hailey H ChoiFrom the Department of Radiology, Einstein Medical Center, 5501 Old York Rd, Levy Ground, Philadelphia, PA 19141 (S.K.R.); Department of Radiology, University of Texas Southwestern Medical Center, Dallas, Tex (D.T.F.); Department of Radiology, Northwestern Memorial Hospital, Chicago, Ill (H.G.); Department of Radiology, Royal Perth Hospital, Perth, Australia (J.H.S.); Department of Radiology, Stanford University School of Medicine, Stanford, Calif (H.H.C.); Department of Radiology, University of Michigan Health System, Ann Arbor, Mich (K.E.M., A.P.W.); Department of Radiology and Biomedical Imaging, University of California-San Francisco, San Francisco, Calif (T.A.M.); Department of Radiology, Mayo Clinic, Phoenix, Ariz (N.D.); Department of Radiology (M.K.O., Y.K.) and Liver Imaging Group, Department of Radiology (C.B.S.), University of California-San Diego Medical Center, San Diego, Calif; and Department of Radiology, Stanford University Medical Center, Stanford, Calif (A.K.).
Katherine E MaturenFrom the Department of Radiology, Einstein Medical Center, 5501 Old York Rd, Levy Ground, Philadelphia, PA 19141 (S.K.R.); Department of Radiology, University of Texas Southwestern Medical Center, Dallas, Tex (D.T.F.); Department of Radiology, Northwestern Memorial Hospital, Chicago, Ill (H.G.); Department of Radiology, Royal Perth Hospital, Perth, Australia (J.H.S.); Department of Radiology, Stanford University School of Medicine, Stanford, Calif (H.H.C.); Department of Radiology, University of Michigan Health System, Ann Arbor, Mich (K.E.M., A.P.W.); Department of Radiology and Biomedical Imaging, University of California-San Francisco, San Francisco, Calif (T.A.M.); Department of Radiology, Mayo Clinic, Phoenix, Ariz (N.D.); Department of Radiology (M.K.O., Y.K.) and Liver Imaging Group, Department of Radiology (C.B.S.), University of California-San Diego Medical Center, San Diego, Calif; and Department of Radiology, Stanford University Medical Center, Stanford, Calif (A.K.).
Ashish P WasnikFrom the Department of Radiology, Einstein Medical Center, 5501 Old York Rd, Levy Ground, Philadelphia, PA 19141 (S.K.R.); Department of Radiology, University of Texas Southwestern Medical Center, Dallas, Tex (D.T.F.); Department of Radiology, Northwestern Memorial Hospital, Chicago, Ill (H.G.); Department of Radiology, Royal Perth Hospital, Perth, Australia (J.H.S.); Department of Radiology, Stanford University School of Medicine, Stanford, Calif (H.H.C.); Department of Radiology, University of Michigan Health System, Ann Arbor, Mich (K.E.M., A.P.W.); Department of Radiology and Biomedical Imaging, University of California-San Francisco, San Francisco, Calif (T.A.M.); Department of Radiology, Mayo Clinic, Phoenix, Ariz (N.D.); Department of Radiology (M.K.O., Y.K.) and Liver Imaging Group, Department of Radiology (C.B.S.), University of California-San Diego Medical Center, San Diego, Calif; and Department of Radiology, Stanford University Medical Center, Stanford, Calif (A.K.).
Tara A MorganFrom the Department of Radiology, Einstein Medical Center, 5501 Old York Rd, Levy Ground, Philadelphia, PA 19141 (S.K.R.); Department of Radiology, University of Texas Southwestern Medical Center, Dallas, Tex (D.T.F.); Department of Radiology, Northwestern Memorial Hospital, Chicago, Ill (H.G.); Department of Radiology, Royal Perth Hospital, Perth, Australia (J.H.S.); Department of Radiology, Stanford University School of Medicine, Stanford, Calif (H.H.C.); Department of Radiology, University of Michigan Health System, Ann Arbor, Mich (K.E.M., A.P.W.); Department of Radiology and Biomedical Imaging, University of California-San Francisco, San Francisco, Calif (T.A.M.); Department of Radiology, Mayo Clinic, Phoenix, Ariz (N.D.); Department of Radiology (M.K.O., Y.K.) and Liver Imaging Group, Department of Radiology (C.B.S.), University of California-San Diego Medical Center, San Diego, Calif; and Department of Radiology, Stanford University Medical Center, Stanford, Calif (A.K.).
Nirvikar DahiyaFrom the Department of Radiology, Einstein Medical Center, 5501 Old York Rd, Levy Ground, Philadelphia, PA 19141 (S.K.R.); Department of Radiology, University of Texas Southwestern Medical Center, Dallas, Tex (D.T.F.); Department of Radiology, Northwestern Memorial Hospital, Chicago, Ill (H.G.); Department of Radiology, Royal Perth Hospital, Perth, Australia (J.H.S.); Department of Radiology, Stanford University School of Medicine, Stanford, Calif (H.H.C.); Department of Radiology, University of Michigan Health System, Ann Arbor, Mich (K.E.M., A.P.W.); Department of Radiology and Biomedical Imaging, University of California-San Francisco, San Francisco, Calif (T.A.M.); Department of Radiology, Mayo Clinic, Phoenix, Ariz (N.D.); Department of Radiology (M.K.O., Y.K.) and Liver Imaging Group, Department of Radiology (C.B.S.), University of California-San Diego Medical Center, San Diego, Calif; and Department of Radiology, Stanford University Medical Center, Stanford, Calif (A.K.).
Mary K O'BoyleFrom the Department of Radiology, Einstein Medical Center, 5501 Old York Rd, Levy Ground, Philadelphia, PA 19141 (S.K.R.); Department of Radiology, University of Texas Southwestern Medical Center, Dallas, Tex (D.T.F.); Department of Radiology, Northwestern Memorial Hospital, Chicago, Ill (H.G.); Department of Radiology, Royal Perth Hospital, Perth, Australia (J.H.S.); Department of Radiology, Stanford University School of Medicine, Stanford, Calif (H.H.C.); Department of Radiology, University of Michigan Health System, Ann Arbor, Mich (K.E.M., A.P.W.); Department of Radiology and Biomedical Imaging, University of California-San Francisco, San Francisco, Calif (T.A.M.); Department of Radiology, Mayo Clinic, Phoenix, Ariz (N.D.); Department of Radiology (M.K.O., Y.K.) and Liver Imaging Group, Department of Radiology (C.B.S.), University of California-San Diego Medical Center, San Diego, Calif; and Department of Radiology, Stanford University Medical Center, Stanford, Calif (A.K.).
Yuko KonoFrom the Department of Radiology, Einstein Medical Center, 5501 Old York Rd, Levy Ground, Philadelphia, PA 19141 (S.K.R.); Department of Radiology, University of Texas Southwestern Medical Center, Dallas, Tex (D.T.F.); Department of Radiology, Northwestern Memorial Hospital, Chicago, Ill (H.G.); Department of Radiology, Royal Perth Hospital, Perth, Australia (J.H.S.); Department of Radiology, Stanford University School of Medicine, Stanford, Calif (H.H.C.); Department of Radiology, University of Michigan Health System, Ann Arbor, Mich (K.E.M., A.P.W.); Department of Radiology and Biomedical Imaging, University of California-San Francisco, San Francisco, Calif (T.A.M.); Department of Radiology, Mayo Clinic, Phoenix, Ariz (N.D.); Department of Radiology (M.K.O., Y.K.) and Liver Imaging Group, Department of Radiology (C.B.S.), University of California-San Diego Medical Center, San Diego, Calif; and Department of Radiology, Stanford University Medical Center, Stanford, Calif (A.K.).
Claude B SirlinFrom the Department of Radiology, Einstein Medical Center, 5501 Old York Rd, Levy Ground, Philadelphia, PA 19141 (S.K.R.); Department of Radiology, University of Texas Southwestern Medical Center, Dallas, Tex (D.T.F.); Department of Radiology, Northwestern Memorial Hospital, Chicago, Ill (H.G.); Department of Radiology, Royal Perth Hospital, Perth, Australia (J.H.S.); Department of Radiology, Stanford University School of Medicine, Stanford, Calif (H.H.C.); Department of Radiology, University of Michigan Health System, Ann Arbor, Mich (K.E.M., A.P.W.); Department of Radiology and Biomedical Imaging, University of California-San Francisco, San Francisco, Calif (T.A.M.); Department of Radiology, Mayo Clinic, Phoenix, Ariz (N.D.); Department of Radiology (M.K.O., Y.K.) and Liver Imaging Group, Department of Radiology (C.B.S.), University of California-San Diego Medical Center, San Diego, Calif; and Department of Radiology, Stanford University Medical Center, Stanford, Calif (A.K.).
Aya KamayaFrom the Department of Radiology, Einstein Medical Center, 5501 Old York Rd, Levy Ground, Philadelphia, PA 19141 (S.K.R.); Department of Radiology, University of Texas Southwestern Medical Center, Dallas, Tex (D.T.F.); Department of Radiology, Northwestern Memorial Hospital, Chicago, Ill (H.G.); Department of Radiology, Royal Perth Hospital, Perth, Australia (J.H.S.); Department of Radiology, Stanford University School of Medicine, Stanford, Calif (H.H.C.); Department of Radiology, University of Michigan Health System, Ann Arbor, Mich (K.E.M., A.P.W.); Department of Radiology and Biomedical Imaging, University of California-San Francisco, San Francisco, Calif (T.A.M.); Department of Radiology, Mayo Clinic, Phoenix, Ariz (N.D.); Department of Radiology (M.K.O., Y.K.) and Liver Imaging Group, Department of Radiology (C.B.S.), University of California-San Diego Medical Center, San Diego, Calif; and Department of Radiology, Stanford University Medical Center, Stanford, Calif (A.K.).

Funding

Molecular Imaging Methods for the Detection of Pancreatic Ductal AdenocarcinomaU01CA210020 · NCI · STANFORD UNIVERSITY · PI IAGARU, ANDREI, PARK, WALTER GWANG-UP · 2017 to 2021
$4.1M
Three-Dimensional Multi-Parametric Ultrasound for Monitoring Therapy of Liver MetastasisR01CA195443 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Ahmed El Kaffas · 2016 to 2026
$3.6M
CONTRAST-ENHANCED ULTRASOUND EVALUATION OF FOCAL LIVER LESIONS IN PATIENTS WITH CIRRHOSIS OR OTHER RISK FACTORS FOR DEVELOPING HCCR01CA215520 · NCI · THOMAS JEFFERSON UNIVERSITY · PI LYSHCHIK, ANDREJ · 2017 to 2020
$2.4M
NCI NIH HHS R01 CA195443NCI NIH HHS R01 CA215520NCI NIH HHS U01 CA210020
6 · The paper itself

Abstract

The US Liver Imaging Reporting and Data System (LI-RADS) was released in 2017 and is the newest of the four American College of Radiology (ACR) LI-RADS algorithms. US LI-RADS provides standardized terminology, technical recommendations, and a reporting framework for US examinations performed for screening or surveillance in patients at risk for developing hepatocellular carcinoma (HCC). The appropriate patient population for screening and surveillance includes individuals who are at risk for developing HCC but do not have known or suspected cancer. This includes patients with cirrhosis from any cause and subsets of patients with chronic hepatitis B virus infection in the absence of cirrhosis. In an HCC screening or surveillance study, US LI-RADS recommends assigning two scores that apply to the entire study: the US category, which determines follow-up, and a visualization score, which communicates the expected level of sensitivity of the examination but does not affect management. Three US categories are possible: US-1 negative, a study with no evidence of HCC; US-2 subthreshold, a study in which an observation less than 10 mm is depicted that is not definitely benign; and US-3 positive, a study in which an observation greater than or equal to 10 mm or a new thrombus in vein is identified, for which diagnostic contrast material-enhanced imaging is recommended. Three visualization scores are possible: A (no or minimal limitations), B (moderate limitations), and C (severe limitations).

Indexed as

AlgorithmsData SystemsUltrasonographyAgedCarcinoma, HepatocellularEarly Detection of CancerFemaleHumansLiverLiver DiseasesLiver NeoplasmsMaleMiddle AgedPopulation Surveillance

Identifiers

PMID31059393
PMCPMC6542628

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.