Evidence map›Paper›PMID 31058865›Full record

ArticleBrain sciences2019

Preserved Cerebral Oxygen Metabolism in Astrocytic Dysfunction: A Combination Study of

Carla Mari Macaisa, Tadashi Watabe, Yuwei Liu, Victor Romanov, Yasukazu Kanai, Genki Horitsugi, Hiroki Kato, Eku Shimosegawa, Jun Hatazawa

Open access · goldAbstract read
In one paragraph

Article in Brain sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. More than just summed neuronal activity: how multiple cell types shape the BOLD response.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Carla Mari MacaisaDepartment of Nuclear Medicine and Tracer Kinetics, Osaka University Graduate School of Medicine, Suita 565-0871, Japan. carlamari_md@yahoo.com.
Tadashi WatabeDepartment of Nuclear Medicine and Tracer Kinetics, Osaka University Graduate School of Medicine, Suita 565-0871, Japan. watabe@tracer.med.osaka-u.ac.jp.
Yuwei LiuDepartment of Nuclear Medicine and Tracer Kinetics, Osaka University Graduate School of Medicine, Suita 565-0871, Japan. liu@tracer.med.osaka-u.ac.jp.
Victor RomanovDepartment of Nuclear Medicine and Tracer Kinetics, Osaka University Graduate School of Medicine, Suita 565-0871, Japan. romanov@tracer.med.osaka-u.ac.jp.
Yasukazu KanaiDepartment of Molecular Imaging in Medicine, Osaka University Graduate School of Medicine,Suita 565-0871, Japan. ykanai@mi.med.osaka-u.ac.jp.
Genki HoritsugiDepartment of Nuclear Medicine and Tracer Kinetics, Osaka University Graduate School of Medicine, Suita 565-0871, Japan. horitsugi@tracer.med.osaka-u.ac.jp.
Hiroki KatoDepartment of Nuclear Medicine and Tracer Kinetics, Osaka University Graduate School of Medicine, Suita 565-0871, Japan. kato@tracer.med.osaka-u.ac.jp.
Eku ShimosegawaDepartment of Molecular Imaging in Medicine, Osaka University Graduate School of Medicine,Suita 565-0871, Japan. eku@tracer.med.osaka-u.ac.jp.
Jun HatazawaDepartment of Nuclear Medicine and Tracer Kinetics, Osaka University Graduate School of Medicine, Suita 565-0871, Japan. hatazawa@tracer.med.osaka-u.ac.jp.
The University of Osaka · JP

Funding

Ministry of Education, Culture, Sports, Science and Technology (MEXT), Japan 15K19787
6 · The paper itself

Abstract

Fluorocitrate (FC) is a specific metabolic inhibitor of the tricarboxylic acid (TCA) cycle in astrocytes. The purpose of this study was to evaluate whether inhibition of the astrocyte TCA cycle by FC would affect the oxygen metabolism in the rat brain. At 4 h after the intracranial FC injection, the rats (

Indexed as

14C-acetate15O-gas PETastrocytecerebral blood flowcerebral metabolic rate of oxygenfluorocitrateoxygen consumptionTCA cycle

Identifiers

PMID31058865
PMCPMC6562644
OpenAlexW2943512560

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.