Evidence map›Paper›PMID 31058262›Full record

ArticleJournal of oncology research and therapy2017

Oral Squamous Cell Carcinomas are Associated with Poorer Outcome with Increasing Ages.

Tarinee Lubpairee, Catherine F Poh, Denise M Laronde, Miriam P Rosin, Lewei Zhang

Open access · greenAbstract read
In one paragraph

Article in Journal of oncology research and therapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 69% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Tarinee LubpaireeDepartment of Oral Biological and Medical Sciences, Faculty of Dentistry, The University of British Columbia (BC), Vancouver, Canada.
Catherine F PohDepartment of Oral Biological and Medical Sciences, Faculty of Dentistry, The University of British Columbia (BC), Vancouver, Canada.
Denise M LarondeDepartment of Oral Biological and Medical Sciences, Faculty of Dentistry, The University of British Columbia (BC), Vancouver, Canada.
Miriam P RosinBC Oral Biopsy Service, Vancouver General Hospital, Vancouver, Canada.
Lewei ZhangDepartment of Oral Biological and Medical Sciences, Faculty of Dentistry, The University of British Columbia (BC), Vancouver, Canada.
BC Cancer Agency · CASimon Fraser University · CA

Funding

CLONAL CHANGES IN ORAL LESIONS OF HIGH-RISK PATIENTSR01DE013124 · NIDCR · BRITISH COLUMBIA CANCER AGENCY · PI ROSIN, MIRIAM P. · 1999 to 2007
$2.1M
Optical Techniques and Oral Precancer ManagementR01DE017013 · NIDCR · BRITISH COLUMBIA CANCER AGENCY · PI ROSIN, MIRIAM P. · 2005 to 2009
$1.9M
NIDCR NIH HHS R01 DE013124NIDCR NIH HHS R01 DE017013
6 · The paper itself

Abstract

objectives1.1.Although oral cancers traditionally occur in people between the age of 50 and 70, there are increasing incidences of this disease in younger and very old people. Objectives: to compare the demographics, habits, clinicopathological features, treatment and outcome of oral cancer in three age groups of patients: Young (≤ 45), Traditional (46 to 75), and Old (> 75). SUBJECTS: 1.2.Primary oral cancers (393 patients) in a longitudinal study were used.

results1.3.Significant differences were noted in ethnicity (fewer Caucasian patients in Young), tobacco habit (more non-smokers in Young), location of cancer (more at tongue for Young and more at low-risk sites for Old) and treatment (more surgery for Young). Compared to Young (univariate analysis), Traditional and Old showed a 3- and 4.5-fold increase in local recurrences respectively; 1.9- and 2.7-fold increase in regional metastasis; 3.1- and 5.4-fold increase in death due to disease; and a 3.4- and 6.6-fold decrease in overall survival. Compared to Young (multivariate analysis), Traditional and Old showed a 2.4- and 3.3-fold increase in local recurrence; 2.7- and 5.4-fold increase in disease-specific survival; and 2.8- and 6.5-fold decrease in overall survival.

conclusion1.4.Oral cancer in different age groups showed differing ethnicity, habit, location, treatment and outcome.

Identifiers

PMID31058262
PMCPMC6498857
OpenAlexW2980038738

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.