ArticleBioMed research international2019
Impact of Fibromyalgia on Alpha-2 EEG Power Spectrum in the Resting Condition: A Descriptive Correlational Study.
Article in BioMed research international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Clinical, neurophysiological and neurochemical effects of non-invasive electrical brain stimulation in fibromyalgia syndrome-a systematic review and meta-analysis.Frontiers in pain research (Lausanne, Switzerland) · 2025Pooled it
- Comparison of two tDCS protocols on pain and EEG alpha-2 oscillations in women with fibromyalgia.Scientific reports · 2020Trial
- Electroencephalography research in neuropathic pain (Review).Molecular medicine reports · 2026Review
- Multivariate Pattern Analysis Identifies Potential Intertrial Resting-State EEG Biomarkers in Fibromyalgia.The European journal of neuroscience · 2026Article
- Efficacy of Acupuncture in Patients with Fibromyalgia Syndrome: A Meta-Analysis.Journal of pain research · 2026Review
- Peak alpha frequency is associated with pain severity in Long COVID patients with new-onset chronic pain.Frontiers in pain research (Lausanne, Switzerland) · 2026Article
- Functional analysis within latent states: A novel framework for analysing functional time series data.PloS one · 2025Article
- EEG connectivity features associated with fibromyalgia revealed by machine learning.Frontiers in pain research (Lausanne, Switzerland) · 2025Article
- Distinct resting state neural activity in chronic pain patients who respond to transcranial electric stimulation for pain relief.Frontiers in human neuroscience · 2025Article
- Effects of Different Transcranial Direct Current Stimulation Intensities over Dorsolateral Prefrontal Cortex on Brain Electrical Activity and Heart Rate Variability in Healthy and Fibromyalgia Women: A Randomized Crossover Trial.Journal of clinical medicine · 2024Article
- Can electroencephalography (EEG) identify the different dimensions of pain in fibromyalgia? A pilot study.BMC musculoskeletal disorders · 2024Article
- Evaluating the effectiveness of neurofeedback in chronic pain management: a narrative review.Frontiers in psychology · 2024Review
- The Behavior of Muscle Oxygen Saturation, Oxy and Deoxy Hemoglobin during a Fatigue Test in Fibromyalgia.Biomedicines · 2023Article
- In search of a composite biomarker for chronic pain by way of EEG and machine learning: where do we currently stand?Frontiers in neuroscience · 2023Review
- Embodied strategies for public speaking anxiety: evaluation of the Corp-Oral program.Frontiers in human neuroscience · 2023Article
- Neuroimaging Assessment of Pain.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2022Review
- Impact of being physically active on the brain electrocortical activity, brain volumetry and performance in the Stroop color and word test in women with fibromyalgia.Scientific reports · 2022Article
- Effects of Transcranial Direct Current Stimulation on Brain Electrical Activity, Heart Rate Variability, and Dual-Task Performance in Healthy and Fibromyalgia Women: A Study Protocol.Behavioral sciences (Basel, Switzerland) · 2022Article
- Sound-Induced Flash Illusions Support Cortex Hyperexcitability in Fibromyalgia.Pain research & management · 2022Article
- Effect of Implantable Electrical Nerve Stimulation on Cortical Dynamics in Patients With Herpes Zoster-Related Pain: A Prospective Pilot Study.Frontiers in bioengineering and biotechnology · 2022Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
objectiveThe objective of this prospective cross-sectional study was to analyze the differences between patients with fibromyalgia and non-pain controls in terms of EEG power in the eyes-closed resting state. This study also aims to evaluate potential correlations between EEG power and subjective pain.
methodsThe fibromyalgia patients were recruited by the Extremadura Association of Fibromyalgia (AFIBROEX) in Cáceres, Spain. Age- and sex-matched healthy controls (1:1 ratio) were recruited from university facilities and people close to the AFIBROEX by public calls. All underwent EEG during a 1-minute resting period with their eyes closed. The theta, alpha-1, alpha-2, beta-1, beta-2, and beta-3 frequency bands were analyzed by using EEGLAB. Self-reported visual analog scale pain scores were determined just prior to EEG.
resultsA total of 62 women participated in the study, 31 of them diagnosed with fibromyalgia and 31 healthy controls. Fibromyalgia group exhibited a significantly lower alpha-2 in C4, T3, P4, Pz, and O2 compared to the healthy controls. Interestingly, pain correlated negatively with alpha-2 in Cz, P4, and Pz only in the fibromyalgia group.
conclusionThe fibromyalgia group exhibited decrease alpha-2 power in central, temporoparietal, and occipital brain areas. Furthermore, higher values of pain correlated with lower level of alpha-2 power in Cz, P4, and Pz. These findings may point the importance of alpha-2 power in pain in women with fibromyalgia.
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