Evidence map›Paper›PMID 31057971›Full record

ArticleProstate cancer2019

The Biopsychosocial Burden of Prostate Biopsy at the Time of Its Indication, Procedure, and Pathological Report.

Walker W Laranja, Brunno C F Sanches, Brunno R I Voris, João C C Alonso, Fabiano A Simões, Ronald F Rejowski, Leonardo O Reis

Registry-linked trialAbstract read
In one paragraph

Article in Prostate cancer, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03783741 (The Biopsychosocial Burden of Prostate Biopsy at the Time of Its Indication, Procedure, and Pathological Report), which is not on this map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03783741 completednot on this map

The Biopsychosocial Burden of Prostate Biopsy at the Time of Its Indication, Procedure, and Pathological Report

TypeobservationalSponsorUniversity of Campinas, BrazilRan2014 to 2016Enrolled47ConditionsProstate CancerArmsQuestionnaire
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Walker W LaranjaUniversity of Campinas (Unicamp), Campinas, São Paulo, Brazil.ORCID 0000-0002-8705-6853
Brunno C F SanchesUniversity of Campinas (Unicamp), Campinas, São Paulo, Brazil.
Brunno R I VorisUniversity of Campinas (Unicamp), Campinas, São Paulo, Brazil.
João C C AlonsoUniversity of Campinas (Unicamp), Campinas, São Paulo, Brazil.
Fabiano A SimõesUniversity of Campinas (Unicamp), Campinas, São Paulo, Brazil.
Ronald F RejowskiUniversity of Campinas (Unicamp), Campinas, São Paulo, Brazil.ORCID 0000-0001-6519-9514
Leonardo O ReisUniversity of Campinas (Unicamp), Campinas, São Paulo, Brazil.ORCID 0000-0003-2092-414X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo explore the burden of prostate biopsy at the time of its indication, procedure, and pathological report in the prostate cancer-screening scenario that is neglected and underestimated in the literature.

methodsProstate biopsy was offered to 47 consecutive patients with prostate-specific antigen (PSA) over 4 ng/dl or suspicious digital rectal examination (DRE) of whom 16 had undergone a biopsy. Comprehensive validated questionnaires at Time 0 (prebiopsy), Time 1 (before diagnosis, 20 days after biopsy), and Time 2 (after diagnosis, 40 days after biopsy) accessed patients' erectile (IIEF-5) and voiding (IPSS) functions, Beck scales measured anxiety (BAI), hopelessness (BHS), and depression (BDI), added to the emotional thermometers including five visual analog scales for distress, anxiety, depression, anger, and need for help. The Mann-Whitney or Friedman tests were obtained among times and studied variables.

resultsProstate biopsy did not significantly impact patients' erectile and voiding functions while a higher Beck anxiety index (BAI) was observed at Time 0 (6.89 ± 6.33) compared to Time 1 (4.83 ± 2.87),

conclusionsTo be considered in patients' counseling and care, the current study supports the hypothesis that the peak burden of prostate biopsy occurs at the time of its indication and might be higher for those experiencing rebiopsy, significantly impacting patients' psychosocial domains. TRIAL APPROVAL: This trial is registered under number NCT03783741.

Identifiers

PMID31057971
PMCPMC6463558

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.