Evidence map›Paper›PMID 31057921›Full record

ArticleMicrosystems & nanoengineering2018

High-throughput multiplexed fluorescence-activated droplet sorting.

Ouriel Caen, Simon Schütz, M S Suryateja Jammalamadaka, Jérémy Vrignon, Philippe Nizard, Tobias M Schneider, Jean-Christophe Baret, Valérie Taly

Abstract read
In one paragraph

Article in Microsystems & nanoengineering, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Confocal Absorbance-Activated Droplet Sorting (cAADS) for Enzyme Engineering.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Tutorial on Lateral Dielectrophoretic Manipulations in Microfluidic Systems.IEEE transactions on biomedical circuits and systems · 2023
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ouriel Caen1INSERM UMR-S1147, CNRS SNC5014, Paris Descartes University, Equipe labellisée Ligue Nationale contre le cancer, Paris, France.
Simon Schütz2Emergent Complexity in Physical Systems Laboratory (ECPS), Ecole Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland.
M S Suryateja Jammalamadaka1INSERM UMR-S1147, CNRS SNC5014, Paris Descartes University, Equipe labellisée Ligue Nationale contre le cancer, Paris, France.
Jérémy Vrignon3CNRS, University Bordeaux, CRPP, UMR 5031, 115 Avenue Schweitzer, 33600 Pessac, France.
Philippe Nizard1INSERM UMR-S1147, CNRS SNC5014, Paris Descartes University, Equipe labellisée Ligue Nationale contre le cancer, Paris, France.
Tobias M Schneider2Emergent Complexity in Physical Systems Laboratory (ECPS), Ecole Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland.
Jean-Christophe Baret3CNRS, University Bordeaux, CRPP, UMR 5031, 115 Avenue Schweitzer, 33600 Pessac, France.
Valérie Taly1INSERM UMR-S1147, CNRS SNC5014, Paris Descartes University, Equipe labellisée Ligue Nationale contre le cancer, Paris, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fluorescence-activated droplet sorting (FADS) is one of the most important features provided by droplet-based microfluidics. However, to date, it does not allow to compete with the high-throughput multiplexed sorting capabilities offered by flow cytometery. Here, we demonstrate the use of a dielectrophoretic-based FADS, allowing to sort up to five different droplet populations simultaneously. Our system provides means to select droplets of different phenotypes in a single experimental run to separate initially heterogeneous populations. Our experimental results are rationalized with the help of a numerical model of the actuation of droplets in electric fields providing guidelines for the prediction of sorting designs for upscaled or downscaled microsystems.

Identifiers

PMID31057921
PMCPMC6220162

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.