Using airbrushes to pattern reagents for microarrays and paper-fluidic devices.

Christopher L Cassano, Teodor Z Georgiev, Z Hugh Fan

Abstract read

In one paragraph

Article in Microsystems & nanoengineering, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Christopher L CassanoInterdisciplinary Microsystems Group, Department of Mechanical and Aerospace Engineering, University of Florida, P.O. Box 116250, Gainesville, FL 32611, USA.

Teodor Z GeorgievInterdisciplinary Microsystems Group, Department of Mechanical and Aerospace Engineering, University of Florida, P.O. Box 116250, Gainesville, FL 32611, USA.

Z Hugh FanInterdisciplinary Microsystems Group, Department of Mechanical and Aerospace Engineering, University of Florida, P.O. Box 116250, Gainesville, FL 32611, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report using an airbrush to pattern a number of reagents, including small molecules, proteins, DNA, and conductive microparticles, onto a variety of mechanical substrates such as paper and glass. Airbrushing is more economical and easier to perform than many other patterning methods available (for example, inkjet printing). In this work, we investigated the controllable parameters that affect patterned line width and studied their mechanisms of action, and we provide examples of possible patterns. This airbrushing approach allowed us to pattern lines and dot arrays from hundreds of μm to tens of mm with length scales comparable to those of other patterning methods. Two applications, enzymatic assays and DNA hybridization, were chosen to demonstrate the compatibility of the method with biomolecules. This airbrushing method holds promise in making paper-based platforms less expensive and more accessible.

Indexed as

airbrushchemiluminescencefabricationlateral flow assaysmicroarrayspaper-fluidics

Identifiers

PMID31057881

DOI10.1038/micronano.2017.55

PMCPMC6445023

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.