Evidence map›Paper›PMID 31057784›Full record

ArticleStroke research and treatment2019

Cognitive and Emotional Impairment after Minor Stroke and Non-ST-Elevation Myocardial Infarction (NSTEMI): A Prevalence Study.

Åse Hagen Morsund, Hanne Ellekjær, Arne Gramstad, Magnus Tallaksen Reiestad, Rune Midgard, Sigrid Botne Sando, Egil Jonsbu, Halvor Næss

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Article in Stroke research and treatment, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  3. Review
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Åse Hagen MorsundDepartment of Neurology, Møre and Romsdal Health Trust, Molde hospital, Molde and Department of Neuromedicine and Movement Science, Norwegian University of Science and Technology, Trondheim, Norway.ORCID 0000-0003-4890-9654
Hanne EllekjærDepartment of Neuromedicine and Movement Science, Norwegian University of Science and Technology, Trondheim and Stroke Unit, Department of Internal Medicine, St Olavs hospital, University Hospital of Trondheim, Norway.
Arne GramstadDepartment of Neurology, Haukeland University Hospital and Department of Biological and Medical Psychology, University of Bergen, Norway.
Magnus Tallaksen ReiestadDepartment of psychiatry, Møre and Romsdal Health Trust, Molde hospital, Molde, Norway.
Rune MidgardDepartment of Neurology, Møre and Romsdal Health Trust, Molde hospital, Molde and Unit for Applied Clinical Research, Norwegian University of Science and Technology, Trondheim, Norway.ORCID 0000-0002-6096-726X
Sigrid Botne SandoDepartment of Neuromedicine and Movement Science, Norwegian University of Science and Technology, Trondheim and Department of neurology, St Olavs hospital, University Hospital of Trondheim, Norway.
Egil JonsbuDepartment of Psychiatry, Møre og Romsdal Health Trust and Department of Mental Health, Norwegian University of Science and Technology, Trondheim, Norway.
Halvor NæssDepartment of neurology, Haukeland University Hospital, Centre for age-related medicine, Stavanger University Hospital, Institute of Clinical Medicine, University of Bergen, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo study the prevalence of cognitive and emotional impairment following a minor ischemic stroke compared to an age-matched group with non-ST-elevation myocardial infarction (NSTEMI).

methodsWe included patients aged 18-70 years with a minor ischemic stroke defined as modified Rankin Scale (mRS) 0-2 at day 7 or at discharge if before and age-matched NSTEMI patients with the same functional mRS. We applied a selection of cognitive tests and the patients completed a questionnaire comprising of Hospital Anxiety and Depression scale (HADS) and Fatigue Severity Scale (FSS) at follow-up 12 months after the vascular event. Results of cognitive tests were also compared to normative data.

results325 ischemic stroke and 144 NSTEMI patients were included. There was no significant difference in cognitive functioning between ischemic stroke and NSTEMI patients. Minor stroke patients and to a lesser extent NSTEMI patients scored worse on more complex cognitive functions including planning and implementation of activities compared to validated normative data. For the minor stroke patients the location of the ischemic lesion had no influence on the result. The prevalence of anxiety, depression, and fatigue was significantly higher in the stroke group compared to the NSTEMI group. Depression was independently associated with reduced cognitive function. DISCUSSION AND

conclusionMinor ischemic stroke patients, and to lesser degree NSTEMI patients, had reduced cognitive function compared to normative data, especially executive functioning, on 12-month follow-up. The difference in cognitive function between stroke and NSTEMI patients was not significant. Depression was associated with low scores on cognitive tests highlighting the need to adequately address emotional sequelae when considering treatment options for cognitive disabilities.

Identifiers

PMID31057784
PMCPMC6463585

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