Evidence map›Paper›PMID 31057776›Full record

ArticleChemical science2019

Biosynthetic reconstitution of deoxysugar phosphoramidate metalloprotease inhibitors using an N-P-bond-forming kinase.

Alexandra Baulig, Irina Helmle, Marius Bader, Felix Wolf, Andreas Kulik, Arwa Al-Dilaimi, Daniel Wibberg, Jörn Kalinowski, Harald Gross, Leonard Kaysser

Abstract read
In one paragraph

Article in Chemical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. ThiF-Like Enzyme Chemistry in Primary and Secondary Metabolism.Chembiochem : a European journal of chemical biology · 2025
    Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Alexandra BauligDepartment of Pharmaceutical Biology , Pharmaceutical Institute , University of Tübingen , 72076 Tübingen , Germany . Email: leonard.kaysser@uni-tuebingen.de.
Irina HelmleDepartment of Pharmaceutical Biology , Pharmaceutical Institute , University of Tübingen , 72076 Tübingen , Germany . Email: leonard.kaysser@uni-tuebingen.de.
Marius BaderDepartment of Pharmaceutical Biology , Pharmaceutical Institute , University of Tübingen , 72076 Tübingen , Germany . Email: leonard.kaysser@uni-tuebingen.de.
Felix WolfDepartment of Pharmaceutical Biology , Pharmaceutical Institute , University of Tübingen , 72076 Tübingen , Germany . Email: leonard.kaysser@uni-tuebingen.de.
Andreas KulikInterfaculty Institute for Microbiology and Infection Medicine Tübingen (IMIT) , Microbiology/Biotechnology , University of Tübingen , 72076 Tübingen , Germany.ORCID 0000-0002-6914-7313
Arwa Al-DilaimiCenter for Biotechnology (CeBiTec) , Bielefeld University , 33615 Bielefeld , Germany.
Daniel WibbergCenter for Biotechnology (CeBiTec) , Bielefeld University , 33615 Bielefeld , Germany.
Jörn KalinowskiCenter for Biotechnology (CeBiTec) , Bielefeld University , 33615 Bielefeld , Germany.ORCID 0000-0002-9052-1998
Harald GrossDepartment of Pharmaceutical Biology , Pharmaceutical Institute , University of Tübingen , 72076 Tübingen , Germany . Email: leonard.kaysser@uni-tuebingen.de.ORCID 0000-0002-0731-821X
Leonard KaysserDepartment of Pharmaceutical Biology , Pharmaceutical Institute , University of Tübingen , 72076 Tübingen , Germany . Email: leonard.kaysser@uni-tuebingen.de.ORCID 0000-0002-3943-993X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phosphoramidon is a potent metalloprotease inhibitor and a widespread tool in cell biology research. It contains a dipeptide backbone that is uniquely linked to a 6-deoxysugar

Identifiers

PMID31057776
PMCPMC6482885

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.