Evidence map›Paper›PMID 31057722›Full record

ArticleAvicenna journal of medical biotechnology

Single Nucleotide Polymorphism of

Azadeh Mohamadhosseini, Reza Mansouri, Ali Javinani, Amir Ashraf Ganjouei, Massoumeh Akhlaghi, Saeed Aslani, Elham Hamzeh, Ahmadreza Jamshidi, Nooshin Ahmadzadeh, Mahdi Mahmoudi

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in Avicenna journal of medical biotechnology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Genetic association between theExperimental and therapeutic medicine · 2022
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Azadeh MohamadhosseiniDepartment of Immunology, Faculty of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Reza MansouriDepartment of Immunology, Faculty of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Ali JavinaniRheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Amir Ashraf GanjoueiRheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Massoumeh AkhlaghiRheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Saeed AslaniRheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Elham HamzehRheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Ahmadreza JamshidiRheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Nooshin AhmadzadehRheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Mahdi MahmoudiRheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Tehran University of Medical Sciences · IRShahid Sadoughi University of Medical Sciences and Health Services · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRheumatoid Arthritis (RA) is a debilitating disorder in which the immune system mainly targets the synovial tissue. Janus kinase family including tyrosine kinase 2 (TYK2) is one of the crucial mediators of the downstream signaling pathway of inflammatory cytokines that further contributes to RA pathogenesis. In this study, the association of

methodsIn the present study, 700 RA patients and 700 sex, age and ethnicity-matched healthy individuals as the control group were included. MGB TaqMan real-time allelic discrimination method was used to determine the rs34536443 polymorphism. Rheumatoid factor, anti-cyclic citrullinated peptide antibody, erythrocyte sedimentation rate and C-reactive protein were also measured.

resultsThe frequency of rs34536443 minor allele (C allele) was not different between patients and control group [1.7

conclusionIn the present study, there was not any association between

Indexed as

Rheumatoid arthritisSingle nucleotide polymorphismTYK2 kinase

Identifiers

PMID31057722
PMCPMC6490405
OpenAlexW2948253006

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.