Evidence map›Paper›PMID 31057605›Full record

ArticleFrontiers in genetics2019

Prognostic Role of

Mihyang Ha, Hwan Moon, Dongwook Choi, Wonmo Kang, Ji-Hong Kim, Keon Jin Lee, Dongsu Park, Chi-Dug Kang, Sae-Ock Oh, Myoung-Eun Han and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. TMED family genes and their roles in human diseases.International journal of medical sciences · 2023
    Pooled it
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  18. Cancer genomics & proteomics
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Mihyang HaDepartment of Anatomy, School of Medicine, Pusan National University, Yangsan, South Korea.
Hwan MoonDepartment of Premedicine, School of Medicine, Pusan National University, Yangsan, South Korea.
Dongwook ChoiDivision of Drug Process Development, New Drug Development Center, Osong Medical Innovation Foundation, Cheongju, South Korea.
Wonmo KangDivision of Drug Process Development, New Drug Development Center, Osong Medical Innovation Foundation, Cheongju, South Korea.
Ji-Hong KimDivision of Drug Process Development, New Drug Development Center, Osong Medical Innovation Foundation, Cheongju, South Korea.
Keon Jin LeeDivision of Drug Process Development, New Drug Development Center, Osong Medical Innovation Foundation, Cheongju, South Korea.
Dongsu ParkDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, United States.
Chi-Dug KangDepartment of Biochemistry, Pusan National University School of Medicine, Yangsan, South Korea.
Sae-Ock OhDepartment of Anatomy, School of Medicine, Pusan National University, Yangsan, South Korea.
Myoung-Eun HanDepartment of Anatomy, School of Medicine, Pusan National University, Yangsan, South Korea.
Yun Hak KimDepartment of Anatomy, Biomedical Research Institute, School of Medicine, Pusan National University, Yangsan, South Korea.
Dongjun LeeDepartment of Convergence Medical Science, Pusan National University School of Medicine, Yangsan, South Korea.
Pusan National University · KROsong Medical Innovation Foundation · KRBaylor College of Medicine · US

Funding

Defining periosteal skeletal stem cells and novel migration mechanisms in bone regeneration and repair in vivoR01AR072018 · NIAMS · BAYLOR COLLEGE OF MEDICINE · PI PARK, DONGSU · 2018 to 2023
$2.1M
NIAMS NIH HHS R01 AR072018
6 · The paper itself

Abstract

Transmembrane p24 trafficking protein 3 (TMED3) is a metastatic suppressor in colon cancer and hepatocellular carcinoma. However, its function in the progression of clear cell renal cell carcinoma (ccRCC) is unknown. Here, we report that TMED3 could be a new prognostic marker for ccRCC. Patient data were extracted from cohorts in the Cancer Genome Atlas (TCGA) and the International Cancer Genome Consortium (ICGC). Differential expression of TMED3 was observed between the low stage (Stage I and II) and high stage (Stage III and IV) patients in the TCGA and ICGC cohorts and between the low grade (Grade I and II) and high grade (Grade III and IV) patients in the TCGA cohort. Further, we evaluated

Indexed as

clear cell renal cell carcinomaICGCprognosisTCGATMED3

Identifiers

PMID31057605
PMCPMC6478656
OpenAlexW2936891008

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.