Evidence map›Paper›PMID 31057554›Full record

ArticleFrontiers in immunology2019

Targeting T Cell Activation and Lupus Autoimmune Phenotypes by Inhibiting Glucose Transporters.

Wei Li, Ganlin Qu, Seung-Chul Choi, Caleb Cornaby, Anton Titov, Natalie Kanda, Xiangyu Teng, Haiting Wang, Laurence Morel

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed, 1 pooled it
10.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 1 synthesis or guideline pooled it, 93 citations in OpenAlex.

  1. Pooled it
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  8. Article
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  10. Immunometabolism in systemic lupus erythematosus.Nature reviews. Rheumatology · 2025
    Review
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  12. Energy metabolism in health and diseases.Signal transduction and targeted therapy · 2025
    Review
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  19. Sex-specific differences in ICOSClinical and experimental medicine · 2024
    Article
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7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Wei LiDepartment of Pathology, Immunology and Laboratory Medicine, University of Florida, Gainesville, FL, United States.
Ganlin QuDepartment of Pathology, Immunology and Laboratory Medicine, University of Florida, Gainesville, FL, United States.
Seung-Chul ChoiDepartment of Pathology, Immunology and Laboratory Medicine, University of Florida, Gainesville, FL, United States.
Caleb CornabyDepartment of Pathology, Immunology and Laboratory Medicine, University of Florida, Gainesville, FL, United States.
Anton TitovDepartment of Pathology, Immunology and Laboratory Medicine, University of Florida, Gainesville, FL, United States.
Natalie KandaDepartment of Pathology, Immunology and Laboratory Medicine, University of Florida, Gainesville, FL, United States.
Xiangyu TengDepartment of Pathology, Immunology and Laboratory Medicine, University of Florida, Gainesville, FL, United States.
Haiting WangDepartment of Rheumatology, RenJi Hospital South, School of Medicine, Shanghai Jiaotong University, Shanghai, China.
Laurence MorelDepartment of Pathology, Immunology and Laboratory Medicine, University of Florida, Gainesville, FL, United States.
University of Florida · USRenji Hospital · CN

Funding

Targeting follicular helper CD4 T cells in SLER01AI128901 · NIAID · UNIVERSITY OF FLORIDA · PI MOREL, LAURENCE · 2017 to 2021
$1.8M
NIAID NIH HHS R01 AI128901
6 · The paper itself

Abstract

CD4

Indexed as

Lymphocyte ActivationAnimalsB-LymphocytesDisease Models, AnimalFemaleGlucoseGlycolysisHumansLupus Erythematosus, SystemicMembrane Transport ProteinsMiceMice, TransgenicT-Lymphocytes, Helper-InducerGlucoseMembrane Transport Proteinsglucose transporterglycolysismetabolismsystemic lupus erythematosusT cells

Identifiers

PMID31057554
PMCPMC6478810
OpenAlexW2936501646

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.