ArticleFrontiers in microbiology2019
Gegen Qinlian Decoction Treats Diarrhea in Piglets by Modulating Gut Microbiota and Short-Chain Fatty Acids.
Article in Frontiers in microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.
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Who cites it
50 citing papers in PubMed, 91 citations in OpenAlex.
- Role of gut microbiota metabolites in maintaining intestinal health and preventing weaning-associated diarrhea in piglets.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2026Review
- Chinese Medicine-Derived Natural Compounds and Intestinal Regeneration: Mechanisms and Experimental Evidence.Biomolecules · 2025Review
- Prevalence of chronic diarrhea and its association with obesity in a Chinese community-based population.Chinese medical journal · 2025Article
- Traditional Chinese medicine as a promising choice for future control of PEDV.Virus research · 2025Review
- The role of gut microbiota in diarrhea and its alleviation through microbiota-targeted interventions.Frontiers in microbiology · 2025Review
- A Prospective Observational Study on the Effects ofInfection and drug resistance · 2025Article
- Effect ofFrontiers in microbiology · 2025Article
- Editorial: The role of gut microbiota in animal gastrointestinal diseases.Frontiers in cellular and infection microbiology · 2025Article
- Phytogenic feed additives as natural antibiotic alternatives in animal health and production: A review of the literature of the last decade.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2024Review
- Polysaccharides as Protective Agents against Heavy Metal Toxicity.Foods (Basel, Switzerland) · 2024Review
- Effects of Different Feed Additives on Intestinal Metabolite Composition of Weaned Piglets.Metabolites · 2024Article
- Short Chain Fatty Acids: Essential Weapons of Traditional Medicine in Treating Inflammatory Bowel Disease.Molecules (Basel, Switzerland) · 2024Review
- Research progress of traditional Chinese medicine on the treatment of diarrhea by regulating intestinal microbiota and its metabolites based on renal-intestinal axis.Frontiers in cellular and infection microbiology · 2024Review
- Dietary supplementation with proanthocyanidins and rutin alleviates the symptoms of type 2 diabetes mice and regulates gut microbiota.Frontiers in microbiology · 2024Article
- Effect of Gegen Qinlian Decoction on the regulation of gut microbiota and metabolites in type II diabetic rats.Frontiers in microbiology · 2024Article
- Potential application mechanism of traditional Chinese medicine in treating immune checkpoint inhibitor-induced colitis.Frontiers in immunology · 2024Review
- Competitive Analysis of Rumen and Hindgut Microbiota Composition and Fermentation Function in Diarrheic and Non-Diarrheic Postpartum Dairy Cows.Microorganisms · 2023Article
- Protective Application of Chinese Herbal Compounds and Formulae in Intestinal Inflammation in Humans and Animals.Molecules (Basel, Switzerland) · 2023Review
- Environmental Microplastic Exposure Changes Gut Microbiota in Chickens.Animals : an open access journal from MDPI · 2023Article
- Rutin alleviates colon lesions and regulates gut microbiota in diabetic mice.Scientific reports · 2023Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gut microbiota and its metabolites, short-chain fatty acids (SCFAs), play important roles in diarrheal diseases. Gegen Qinlian decoction (GQD), a Chinese herb formula, has been widely used to treat infectious diarrhea for centuries. However, little is known about the mechanism underlying its efficacy and whether it is mediated by gut microbiota and SCFAs. In this study, the composition of gut microbiota from bacterial diarrheal piglets was assessed using 16S rRNA analysis. The concentrations of fecal SCFAs were determined using a gas chromatography-mass spectrometer (GC-MS). The expression of mucosal pro-inflammatory cytokines in the colon was ascertained. Results showed that GQD reverses the reduction in the richness of gut microbiota, changes its structure, and significantly increases the relative abundances of SCFA-producing bacteria, including
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.