ArticleFrontiers in microbiology2019
Manure and Doxycycline Affect the Bacterial Community and Its Resistome in Lettuce Rhizosphere and Bulk Soil.
Article in Frontiers in microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Spatioseasonal Comparison of Fecal Resistome and Pathogenome of Raccoon Dogs in Korea.EcoHealth · 2026Article
- Biosolids as Safe Fertilizers for Soybean and Maize: Enhanced Nutrition Without Antibiotic Residues or Phenotypic Resistance in Grains.Antibiotics (Basel, Switzerland) · 2025Article
- The Impact of Tetracycline on the Soil Microbiome and the Rhizosphere of Lettuce (International journal of molecular sciences · 2025Article
- Unde venis? Bacterial resistance from environmental reservoirs to lettuce: tracking microbiome and resistome over a growth period.FEMS microbiology ecology · 2024Article
- Resistome Signature and Antibiotic Resistance Mechanisms in Rhizospheric Soil Bacteriomes of Mecca Region, Saudi Arabia: Insights into Impact on Human Health.Life (Basel, Switzerland) · 2024Article
- The Role of Stakeholders' Understandings in Emerging Antimicrobial Resistance: A One Health Approach.Microorganisms · 2023Review
- Functional analysis of bacterial genes accidentally packaged in rhizospheric phageome of the wild plant speciesSaudi journal of biological sciences · 2023Article
- Abundant resistome determinants in rhizosphere soil of the wild plant Abutilon fruticosum.AMB Express · 2023Article
- Horizontal Gene Transfer of Antibiotic Resistance Genes in Biofilms.Antibiotics (Basel, Switzerland) · 2023Review
- Critical transition of soil microbial diversity and composition triggered by plant rhizosphere effects.Frontiers in plant science · 2023Article
- Controlling AMR in the Pig Industry: Is It Enough to Restrict Heavy Metals?International journal of environmental research and public health · 2022Article
- Antimicrobial Resistance in New Zealand-A One Health Perspective.Antibiotics (Basel, Switzerland) · 2022Review
- Biosolids for safe land application: does wastewater treatment plant size matters when considering antibiotics, pollutants, microbiome, mobile genetic elements and associated resistance genes?Environmental microbiology · 2022Article
- Abundant antibiotic resistance genes in rhizobiome of the human edibleFrontiers in microbiology · 2022Article
- Effect of Doxycycline Use in the Early Broiler Production Cycle on the Microbiome.Frontiers in microbiology · 2022Article
- Plant resistome profiling in evolutionary old bog vegetation provides new clues to understand emergence of multi-resistance.The ISME journal · 2021Article
- Gentamicin Adsorption onto Soil Particles Prevents Overall Short-Term Effects on the Soil Microbiome and Resistome.Antibiotics (Basel, Switzerland) · 2021Article
- The distribution of antibiotic resistance genes in chicken gut microbiota commensals.Scientific reports · 2021Article
- Bacterial Inoculants Mitigating Water Scarcity in Tomato: The Importance of Long-TermFrontiers in microbiology · 2021Article
- Exploring the Animal Waste Resistome: The Spread of Antimicrobial Resistance Genes Through the Use of Livestock Manure.Frontiers in microbiology · 2020Review
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Manure application to agricultural soil introduces antibiotic residues and increases the abundance of antibiotic-resistant bacteria (ARB) carrying antibiotic resistance genes (ARGs), often located on mobile genetic elements (MGEs). The rhizosphere is regarded as a hotspot of microbial activity and gene transfer, which can alter and prolong the effects of organic fertilizers containing antibiotics. However, not much is known about the influence of plants on the effects of doxycycline applied to soil via manure. In this study, the effects of manure spiked with or without doxycycline on the prokaryotic community composition as well as on the relative abundance of ARGs and MGEs in lettuce rhizosphere and bulk soil were investigated by means of a polyphasic cultivation-independent approach. Samples were taken 42 days after manure application, and total community DNA was extracted. Besides a pronounced manure effect, doxycycline spiking caused an additional enrichment of ARGs and MGEs. High-throughput quantitative PCR revealed an increase in tetracycline, aminoglycoside, and macrolide-lincosamide-streptogramin B (MLSB) resistance genes associated with the application of manure spiked with doxycycline. This effect was unexpectedly lower in the rhizosphere than in bulk soil, suggesting a faster dissipation of the antibiotic and a more resilient prokaryotic community in the rhizosphere. Interestingly, the tetracycline resistance gene
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