ArticleFrontiers in human neuroscience2019
Sensory Re-weighting for Postural Control in Parkinson's Disease.
Article in Frontiers in human neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 2 of them syntheses that pooled it.
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Who cites it
34 citing papers in PubMed, 2 syntheses or guidelines pooled it, 74 citations in OpenAlex.
- Beyond motor: a systematic review of multisensory integration deficits in Parkinson's disease.Journal of neural transmission (Vienna, Austria : 1996) · 2026Pooled it
- Vestibular Dysfunction in Parkinson's Disease: A Systematic Review of Signs and Symptoms.Movement disorders clinical practice · 2026Pooled it
- Visual perturbation training to reduce visual dependency in Parkinson's disease: A randomized controlled trial.PloS one · 2026Trial
- Strategic alterations of posture are delayed in Parkinson's disease patients during deep brain stimulation.Scientific reports · 2021Trial
- Levodopa-induced dyskinesia provokes inflexible head-pelvis coordination during standing in Parkinson's disease.Clinical biomechanics (Bristol, Avon) · 2026Article
- A Sensory Adaptation Program for Individuals With Mal de Débarquement Syndrome: A Case Series.Journal of neurologic physical therapy : JNPT · 2026Article
- Increased attentional resources may be required to maintain standing balance under conditions of altered visual and somatosensory feedback among healthy adults.Experimental brain research · 2026Article
- Motorist's Disorientation Syndrome-A Narrative Review.Journal of functional morphology and kinesiology · 2026Review
- Balance biomarker for early differentiation of Parkinson's disease and multiple system atrophy with parkinsonian type.Journal of neurology · 2026Article
- Assessment of balance control mechanisms in patient populations using perturbation-based modeling: a narrative review with clinical implications.Frontiers in human neuroscience · 2026Review
- Using Loss of Balance to Understand Postural Instability Associated With Parkinson's Disease.Parkinson's disease · 2026Article
- Interoceptive predictors of daily functioning in aging and their interaction with exteroceptive bodily representations.Frontiers in psychology · 2026Article
- Foot placement coordination is impaired in people with Parkinson's disease.Journal of neuroengineering and rehabilitation · 2025Article
- Sensorimotor incongruence during walking using delayed visual feedback.Psychological research · 2025Article
- The Effect of Sensory Reweighting on Postural Control and Cortical Activity in Parkinson's Disease: A Pilot Study.Archives of rehabilitation research and clinical translation · 2024Article
- Vertical Ground Reaction Forces in Parkinson's Disease: A Speed-Matched Comparative Analysis with Healthy Subjects.Sensors (Basel, Switzerland) · 2023Article
- Cholinergic system correlates of postural control changes in Parkinson's disease freezers.Brain : a journal of neurology · 2023Article
- Margins of postural stability in Parkinson's disease: an application of control theory.Frontiers in bioengineering and biotechnology · 2023Article
- Control of structural redundancy from the head to trunk in the human upright standing revealed using a data-driven approach.Scientific reports · 2022Article
- A Public Data Set With Ground Reaction Forces of Human Balance in Individuals With Parkinson's Disease.Frontiers in neuroscience · 2022Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Postural instability in Parkinson's disease (PD) is characterized by impaired postural responses to transient perturbations, increased postural sway in stance and difficulty transitioning between tasks. In addition, some studies suggest that loss of dopamine in the basal ganglia due to PD results in difficulty in using proprioceptive information for motor control. Here, we quantify the ability of subjects with PD and age-matched control subjects to use and re-weight sensory information for postural control during steady-state conditions of continuous rotations of the stance surface or visual surround. We measure the postural sway of subjects in response to a pseudorandom, surface-tilt stimulus with eyes closed, and in response to a pseudorandom, visual-tilt stimulus. We use a feedback control model of the postural control system to interpret our results, focusing on sensory weighting as a function of stimulus amplitude. We find that subjects with PD can re-weight their dependence upon sensory information in response to changes in surface- or visual-stimulus amplitude. Specifically, subjects with PD behaved like age-matched control subjects by decreasing proprioceptive contribution to stance control with increasing surface-tilt amplitude and decreasing visual contribution with increasing visual-tilt amplitude. However, subjects with PD do not decrease their reliance on proprioception as much as age-matched controls for small increases in surface-stimulus amplitudes. Levodopa medication did not affect sensory re-weighting behaviors for postural control. The impairment in PD subject's ability to respond differently to small changes in surface rotation amplitudes is consistent with an increased threshold for perceiving proprioceptive signals, which may result from decreased signal-to-noise in the dopaminergic pathways associated with sensory processing and/or sensory integration.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.