ReviewFrontiers in molecular neuroscience2019
Relevance of ERK1/2 Post-retrieval Participation on Memory Processes: Insights in Their Particular Role on Reconsolidation and Persistence of Memories.
Review in Frontiers in molecular neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 14 citations in OpenAlex.
- Anandamide blocks spatial memory reconsolidation in male rats through a CB1 receptor dependent mechanism.Psychopharmacology · 2026Article
- Hippocampal ERK2 dimerization regulates inhibitory avoidance memory reconsolidation and synaptic plasticity.iScience · 2026Article
- Disruption of Extracellular Signal-Regulated Kinase Partially Mediates Neonatal Isoflurane Anesthesia-Induced Changes in Dendritic Spines and Cognitive Function in Juvenile Mice.International journal of molecular sciences · 2025Article
- Differential regulation of innate immune system in frontal cortex and hippocampus in a "double-hit" neurodevelopmental model in rats.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2024Article
- On the participation of adenosinergic receptors in the reconsolidation of spatial long-term memory in male rats.Learning & memory (Cold Spring Harbor, N.Y.) · 2023Article
- Mechanisms Underlying Cognitive Impairment Induced by Prenatal Alcohol Exposure.Brain sciences · 2022Review
- Contributions of extracellular-signal regulated kinase 1/2 activity to the memory trace.Frontiers in molecular neuroscience · 2022Review
- Maternal Subclinical Hypothyroidism in Rats Impairs Spatial Learning and Memory in Offspring by Disrupting Balance of the TrkA/p75Molecular neurobiology · 2021Article
- The role of prelimbic and anterior cingulate cortices in fear memory reconsolidation and persistence depends on the memory age.Learning & memory (Cold Spring Harbor, N.Y.) · 2020Article
- Role of prelimbic cortex PKC and PKMζ in fear memory reconsolidation and persistence following reactivation.Scientific reports · 2020Article
- Yizhi Qingxin Formula Extract Ameliorates Cognitive Decline in Aged RatsFrontiers in pharmacology · 2020Article
- Training on an Appetitive Trace-Conditioning Task Increases Adult Hippocampal Neurogenesis and the Expression of Arc, Erk and CREB Proteins in the Dorsal Hippocampus.Frontiers in cellular neuroscience · 2020Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Back in 1968, Misanin and his group posited that reactivation of consolidated memories could support changes in that trace, similar to what might happen during the consolidation process. Not until 2000, when Nader et al. (2000) studied the behavioral effect of a protein synthesis inhibitor on retrieved memories, could this previous statement be taken under consideration once again; suggesting that consolidated memories can become labile after reactivation. The process of strengthening after memory labilization was named memory reconsolidation. In recent years, many studies pointed towards a critical participation of the extracellular signal-regulated kinase (ERK)/mitogen activated protein kinases (MAPKs) pathway in different memory processes (e.g., consolidation, extinction, reconsolidation, among others). In this review article, we will focus on how this system might be modulating the processes triggered after retrieval of well-consolidated memories in mice.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.