Evidence map›Paper›PMID 31057325›Full record

ArticleNutrition and metabolic insights2019

Effects of Pubertal Status and Inflammation on the Use of Ferritin to Define Iron Deficiency in Children With Overweight or Obesity.

Maria Luz Muzzio, Ezequiel S Lozano Chiappe, Laura Kabakian, Florencia Ferraro, Ines Landó, Elizabeth Alonso, Jorgelina Fernández, Soledad Peredo, Lucrecia Brovarone, Maria Pia Santucci and 1 more

Open access · goldAbstract read
In one paragraph

Article in Nutrition and metabolic insights, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Maria Luz MuzzioLaboratorio de Lípidos y Aterosclerosis, Departamento de Bioquímica Clínica, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Buenos Aires, Argentina.
Ezequiel S Lozano ChiappeLaboratorio de Lípidos y Aterosclerosis, Departamento de Bioquímica Clínica, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Buenos Aires, Argentina.
Laura KabakianServicio de Diabetes y Nutrición Infanto-Juvenil, Complejo Médico Churruca Visca, Buenos Aires, Argentina.
Florencia FerraroLaboratorio de Lípidos y Aterosclerosis, Departamento de Bioquímica Clínica, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Buenos Aires, Argentina.
Ines LandóServicio de Diabetes y Nutrición Infanto-Juvenil, Complejo Médico Churruca Visca, Buenos Aires, Argentina.
Elizabeth AlonsoServicio de Diabetes y Nutrición Infanto-Juvenil, Complejo Médico Churruca Visca, Buenos Aires, Argentina.
Jorgelina FernándezServicio de Diabetes y Nutrición Infanto-Juvenil, Complejo Médico Churruca Visca, Buenos Aires, Argentina.
Soledad PeredoServicio de Diabetes y Nutrición Infanto-Juvenil, Complejo Médico Churruca Visca, Buenos Aires, Argentina.
Lucrecia BrovaroneServicio de Diabetes y Nutrición Infanto-Juvenil, Complejo Médico Churruca Visca, Buenos Aires, Argentina.
Maria Pia SantucciServicio de Diabetes y Nutrición Infanto-Juvenil, Complejo Médico Churruca Visca, Buenos Aires, Argentina.
Tomás MeroñoLaboratorio de Lípidos y Aterosclerosis, Departamento de Bioquímica Clínica, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Buenos Aires, Argentina.ORCID https://orcid.org/0000-0002-2673-3494
Universidad de Buenos Aires · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsA worldwide increase in childhood overweight (OW) and obesity (OB) has been reported. OB is an inflammatory state which affects iron metabolism and the sensibility of the tests to detect iron deficiency (ID). Our aim was to evaluate the adequacy of current ferritin cut-offs to define ID in children with OW/OB.

methodsThis cross-sectional study included 152 children (54% girls) aged (median [Q1-Q3]) 11 (8-13) years with OW/OB. Complete blood count and iron metabolism were evaluated. Low ferritin, transferrin saturation (TSat), and anemia were defined by age- and sex-specific cut-offs recommended by National Guidelines. Iron intake was assessed in a subgroup (n = 80) by a 24-hour dietary recall. Analyses were made according to pubertal development and ferritin tertiles.

resultsThe overall prevalence of low ferritin, TSat, and anemia was 2.6%, 23.8%, and 5.2%, respectively. Among pre-pubertal children (n = 87), the frequency of low TSat rose across ferritin tertiles (

conclusionsHigher ferritin cut-off values are required to define ID in children with OW/OB. Such cut-off remains to be validated in larger, multi-ethnic cohorts of children with OW/OB.

Indexed as

childrenferritiniron deficiencyobesitypediatrics

Identifiers

PMID31057325
PMCPMC6452423
OpenAlexW2933976669

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.