Evidence map›Paper›PMID 31057083›Full record

ArticleJournal of the American Heart Association2019

Long-Term Follow-Up of Idiopathic Ventricular Fibrillation in a Pediatric Population: Clinical Characteristics, Management, and Complications.

Antonio Frontera, Konstantinos Vlachos, Takeshi Kitamura, Saagar Mahida, Xavier Pillois, Gerard Fahy, Christelle Marquie, Riccardo Cappato, Graham Stuart, Pascal Defaye and 21 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Guideline
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  3. Review
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  7. Out-of-hospital cardiac arrest due to idiopathic ventricular fibrillation in patients with normal electrocardiograms: results from a multicentre long-term registry.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2019
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

31 authors at 19 institutions in 8 countries.

Antonio Frontera1 Electrophysiology Department, Hopital Haut Lévêque Bordeaux France.
Konstantinos Vlachos1 Electrophysiology Department, Hopital Haut Lévêque Bordeaux France.
Takeshi Kitamura1 Electrophysiology Department, Hopital Haut Lévêque Bordeaux France.
Saagar Mahida3 Department of Cardiac Electrophysiology and Inherited Cardiac Diseases Liverpool Heart and Chest Hospital Liverpool United Kingdom.
Xavier Pillois1 Electrophysiology Department, Hopital Haut Lévêque Bordeaux France.
Gerard Fahy4 Cork University Hospital Cork Ireland.
Christelle Marquie5 Univ. Lille CHU Lille, F-59000 Lille France.
Riccardo Cappato6 Humanitas Clinical and Research Center Rozzano, Milan, Italy and Humanitas University, Department of Biomedical Sciences Milan Italy.
Graham Stuart7 Bristol Heart Institute Bristol United Kingdom.
Pascal Defaye8 Centre Hospitalier University of Grenoble France.
Juan Pablo Kaski9 Centre for Inherited Cardiovascular Diseases Great Ormond Street Hospital London United Kingdom.
Joris Ector11 University Hospital Gasthuisberg Leuven Belgium.
Alice Maltret12 Hôpital Necker Enfants Malades Service de Cardiologie Pédiatrique et Centre de Référence des Maladies Cardiaques Héréditaires Université Paris Descartes Paris France.
Patrice Scanu13 Centre Hospitalier University of Caen France.
Jean-Luc Pasquie14 Centre Hospitalier University of Montpellier France.
Isabelle Deisenhofer15 Herzzentrum München Munich Germany.
Ivan Blankoff16 Centre Hospitalier University of Charleroi Belgium.
Daniel Scherr17 Division of Cardiology Department of Medicine Medical University of Graz Austria.
Martin Manninger17 Division of Cardiology Department of Medicine Medical University of Graz Austria.
Yoshifusa Aizawa18 Niigata University Graduate School of Medical and Dental Science Niigata Japan.
Linda Koutbi19 Hôpital La Timone Marseille France.
Arnaud Denis1 Electrophysiology Department, Hopital Haut Lévêque Bordeaux France.
Thomas Pambrun1 Electrophysiology Department, Hopital Haut Lévêque Bordeaux France.
Philippe Ritter1 Electrophysiology Department, Hopital Haut Lévêque Bordeaux France.
Frederic Sacher1 Electrophysiology Department, Hopital Haut Lévêque Bordeaux France.
Meleze Hocini1 Electrophysiology Department, Hopital Haut Lévêque Bordeaux France.
Philippe Maury20 Centre Hospitalier University of Toulouse France.
Pierre Jaïs1 Electrophysiology Department, Hopital Haut Lévêque Bordeaux France.
Pierre Bordachar1 Electrophysiology Department, Hopital Haut Lévêque Bordeaux France.
Michel Haïssaguerre1 Electrophysiology Department, Hopital Haut Lévêque Bordeaux France.
Nicolas Derval1 Electrophysiology Department, Hopital Haut Lévêque Bordeaux France.
Hôpital Cardiologique du Haut-Lévêque · FRElectrophysiology and Heart Modeling Institute · FRMedical University of Graz · ATCentre Hospitalier Universitaire de Bordeaux · FRCentre Hospitalier Universitaire de Caen · FRCentre Hospitalier Universitaire de Toulouse · FRCork University Hospital · IEDeutsches Herzzentrum der Charité · DEGrand Charleroi Hospital · BEGreat Ormond Street Hospital · GBHôpital de la Timone · FRHumanitas University · ITNIHR Bristol Cardiovascular Biomedical Research Unit · GBUniversitair Ziekenhuis Leuven · BEUniversité de Lille · FRUniversité de Montpellier · FRUniversité Grenoble Alpes · FRUniversité Paris Cité · FRUniversity of Liverpool · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background The natural history and long-term outcome in pediatric patients with idiopathic ventricular fibrillation ( IVF ) are poorly characterized. We sought to define the clinical characteristics and long-term outcomes of a pediatric cohort with an initial diagnosis of IVF . Methods and Results Patients were included from an International Registry of IVF (consisting of 496 patients). Inclusion criteria were: (1) VF with no identifiable cause following comprehensive analysis for ischemic, electrical or structural heart disease and (2) age ≤16 years. These included 54 pediatric IVF cases (age 12.7±3.7 years, 59% male) among whom 28 (52%) had a previous history of syncope (median 2 syncopal episodes [interquartile range 1]). Thirty-six (67%) had VF in situations associated with high adrenergic tone. During a median 109±12 months of follow-up, 31 patients (57%) had recurrence of ventricular arrhythmias, mainly VF . Two patients developed phenotypic expression of an inherited arrhythmia syndrome during follow-up (hypertrophic cardiomyopathy and long QT syndrome, respectively). A total of 15 patients had positive genetic testing for inherited arrhythmia syndromes. Ten patients (18%) experienced device-related complications. Three patients (6%) died, 2 due to VF storm. Conclusions In pediatric patients with IVF , a minority develop a definite clinical phenotype during long-term follow-up. Recurrent VF is common in this patient group.

Indexed as

AdolescentCardiac MyosinsCardiomyopathy, Hypertrophic, FamilialChildDefibrillators, ImplantableElectrocardiographyFemaleHumansLongitudinal StudiesLong QT SyndromeMaleMyosin Heavy ChainsNAV1.5 Voltage-Gated Sodium ChannelPhenotypeRecurrenceRyanodine Receptor Calcium Release ChannelCardiac MyosinsMYH7 protein, humanMyosin Heavy ChainsNAV1.5 Voltage-Gated Sodium ChannelRyanodine Receptor Calcium Release ChannelSCN5A protein, humancomplicationsdefibrillatoridiopathicsyncopeventricular fibrillationventricular tachycardia

Identifiers

PMID31057083
PMCPMC6512137
OpenAlexW2944451021

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.