ArticleACS sensors2019
HIV Detection via a Carbon Nanotube RNA Sensor.
Article in ACS sensors, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- Rational Design of Optical Single-Walled Carbon Nanotube-Based Nanosensors with Biological Recognition Elements.Advanced sensor research · 2026Article
- Single-walled carbon nanotubes sensors: Preparation and bio-application advances.Pharmaceutical science advances · 2025Review
- Effect of Polyelectrolytes on the Photoluminescence of Single-Walled Carbon Nanotubes-Experimental and Simulation Studies.ACS omega · 2025Article
- Strategies, Challenges, and Prospects of Nanoparticles in Gynecological Malignancies.ACS omega · 2024Review
- Development of Optical Nanosensors for Detection of Potassium Ions and Assessment of Their Biocompatibility with Corneal Epithelial Cells.ACS omega · 2024Article
- Development and Evaluation of an Expedited System for Creation of Single Walled Carbon Nanotube Platforms.Carbon letters · 2024Article
- Development of Paper-Based Fluorescent Molecularly Imprinted Polymer Sensor for Rapid Detection of Lumpy Skin Disease Virus.Molecules (Basel, Switzerland) · 2024Article
- Decadal Journey of CNT-Based Analytical Biosensing Platforms in the Detection of Human Viruses.Nanomaterials (Basel, Switzerland) · 2022Review
- Engineering carbon nanotubes for sensitive viral detection.Trends in analytical chemistry : TRAC · 2022Review
- Biosensing with Fluorescent Carbon Nanotubes.Angewandte Chemie (International ed. in English) · 2022Review
- Glycopolymer-Wrapped Carbon Nanotubes Show Distinct Interaction of Carbohydrates With Lectins.Frontiers in chemistry · 2022Article
- The Development of Nanoparticles for the Detection and Imaging of Ovarian Cancers.Biomedicines · 2021Review
- Ultrasensitive biosensing platform based on luminescence quenching ability of fullerenol quantum dots.RSC advances · 2021Article
- En route to single-step, two-phase purification of carbon nanotubes facilitated by high-throughput spectroscopy.Scientific reports · 2021Article
- Quantification of Nitric Oxide Concentration Using Single-Walled Carbon Nanotube Sensors.Nanomaterials (Basel, Switzerland) · 2021Article
- Carbon-based nanomaterials for viral infection management.Biomicrofluidics · 2021Review
- Biosensors for the Detection of Bacterial and Viral Clinical Pathogens.Sensors (Basel, Switzerland) · 2020Review
- Nanoreporter of an Enzymatic Suicide Inactivation Pathway.Nano letters · 2020Article
- A Paper-Based Near-Infrared Optical Biosensor for Quantitative Detection of Protease Activity Using Peptide-Encapsulated SWCNTs.Sensors (Basel, Switzerland) · 2020Article
- Review-Chemical and Biological Sensors for Viral Detection.Journal of the Electrochemical Society · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Viral illnesses remain a significant concern in global health. Rapid and quantitative early detection of viral oligonucleotides without the need for purification, amplification, or labeling would be valuable in guiding successful treatment strategies. Single-walled carbon nanotube-based sensors recently demonstrated optical detection of small, free oligonucleotides in biofluids and in vivo, although proteins diminished sensitivity. Here, we discovered an unexpected phenomenon wherein the carbon nanotube optical response to nucleic acids can be enhanced by denatured proteins. Mechanistic studies found that hydrophobic patches of the denatured protein chain interact with the freed nanotube surface after hybridization, resulting in enhanced shifting of the nanotube emission. We employed this mechanism to detect an intact HIV in serum, resulting in specific responses within minutes. This work portends a route toward point-of-care optical detection of viruses or other nucleic acid-based analytes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.