Evidence map›Paper›PMID 31056769›Full record

ArticleJournal of medical primatology2019

Interferon-Gamma test for the detection of Mycobacterium tuberculosis complex infection in Macaca mulatta and other non-human primates.

JoAnn L Yee, Kamm Prongay, Brodie Miles, Jeremy Smedley, Scott G Hansen, Michael K Axthelm, Amir Ardeshir, Koen K A Van Rompay, Gregory Timmel, Jeffrey A Roberts

Open access · greenAbstract read
In one paragraph

Article in Journal of medical primatology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

JoAnn L YeeCalifornia National Primate Research Center, University of California, Davis, California.ORCID 0000-0002-5514-9836
Kamm ProngayOregon National Primate Research Center, Oregon Health Sciences University, Beaverton, Oregon.
Brodie MilesOregon National Primate Research Center, Oregon Health Sciences University, Beaverton, Oregon.
Jeremy SmedleyOregon National Primate Research Center, Oregon Health Sciences University, Beaverton, Oregon.
Scott G HansenOregon National Primate Research Center, Oregon Health Sciences University, Beaverton, Oregon.
Michael K AxthelmOregon National Primate Research Center, Oregon Health Sciences University, Beaverton, Oregon.
Amir ArdeshirCalifornia National Primate Research Center, University of California, Davis, California.
Koen K A Van RompayCalifornia National Primate Research Center, University of California, Davis, California.
Gregory TimmelOregon National Primate Research Center, Oregon Health Sciences University, Beaverton, Oregon.
Jeffrey A RobertsCalifornia National Primate Research Center, University of California, Davis, California.
Oregon National Primate Research Center · USUniversity of California, Davis · US

Funding

Upgrade of confocal microscopy at the Oregon National Primate Research CenterP51OD011092 · OD · OREGON HEALTH & SCIENCE UNIVERSITY · PI Bonnie J. Nagel · 2012 to 2026
$203.9M
National Institute on Aging (NIA) ColonyP51OD011107 · OD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Simon J. Atkinson · 2012 to 2026
$191.5M
Viral Testing CoreU42OD010990 · OD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Rhonda S Oates, Jeffrey A Roberts · 2012 to 2026
$20.1M
Viral Testing CoreU42OD010426 · OD · OREGON HEALTH & SCIENCE UNIVERSITY · PI Andrew Haertel, Lauren Drew Martin · 2013 to 2026
$6.0M
NIH HHS P51 OD011092NIH HHS P51 OD011107NIH HHS U42 OD010426NIH HHS U42 OD010990
6 · The paper itself

Abstract

We have formatted an assay to detect Mycobacterium tuberculosis complex infections of non-human primates. Commercially available reagents were used to elicit a specific immune response that was measured by interferon-gamma release. Initial evaluation using blood samples from Rhesus macaques experimentally infected with M tuberculosis distinguished infected versus uninfected animals.

Indexed as

Macaca mulattaAnimalsEnzyme-Linked Immunosorbent AssayInterferon-gamma Release TestsMonkey DiseasesMycobacterium tuberculosisTuberculosiscell-mediated immune response (CMI)interferon-gamma release assay (IGRA)purified protein derivative-tuberculin (PPD)

Identifiers

PMID31056769
PMCPMC7012381
OpenAlexW2944307444

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.