ArticleJournal of agricultural and food chemistry2019
A Highly Sensitive SPE Derivatization-UHPLC-MS Approach for Quantitative Profiling of Carotenoid-Derived Dialdehydes from Vegetables.
Article in Journal of agricultural and food chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed, 16 citations in OpenAlex.
- Plant chloroplast stress response: insights from mass spectrometry metabolites analysis.Frontiers in plant science · 2025Article
- IdentifyingFrontiers in plant science · 2022Article
- Carotenoid-derived bioactive metabolites shape plant root architecture to adapt to the rhizospheric environments.Frontiers in plant science · 2022Review
- Exploring the Diversity and Regulation of Apocarotenoid Metabolic Pathways in Plants.Frontiers in plant science · 2021Review
- Apocarotenoids Involved in Plant Development and Stress Response.Frontiers in plant science · 2019Review
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Oxidative cleavage of carotenoids leads to dialdehydes (diapocarotenoids, DIALs) in addition to the widely known apocarotenoids. DIALs are biologically active compounds that presumably impact human health and play different roles in plant development and carotenoid metabolism. However, detection of DIALs in plants is challenging due to their instability, low abundance, and poor ionization efficiency in mass spectrometry. Here, we developed a solid-phase extraction and derivatization protocol coupled with ultrahigh performance liquid chromatography-mass spectrometry for quantitative profiling of DIALs. Our method significantly enhances the sensitivity of DIAL detection with a detection limit of 0.05 pg/mg of dried food materials, allowing unambiguous profiling of 30 endogenous DIALs with C
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