Evidence map›Paper›PMID 31055728›Full record

ArticleJournal of natural medicines2019

Anti-melanin deposition activity and active constituents of Jatropha multifida stems.

So-Yeun Woo, Chin Piow Wong, Nwet Nwet Win, Khine Zar Wynn Lae, Bokyoung Woo, Sherif Adel Elsabbagh, Qian Qian Liu, Hla Ngwe, Hiroyuki Morita

Abstract read
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In one paragraph

Article in Journal of natural medicines, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Bioactive Compounds from Medicinal Plants in Myanmar.Progress in the chemistry of organic natural products · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

So-Yeun WooInstitute of Natural Medicine, University of Toyama, 2630-Sugitani, Toyama, 930-0194, Japan.
Chin Piow WongInstitute of Natural Medicine, University of Toyama, 2630-Sugitani, Toyama, 930-0194, Japan.
Nwet Nwet WinInstitute of Natural Medicine, University of Toyama, 2630-Sugitani, Toyama, 930-0194, Japan.
Khine Zar Wynn LaeDepartment of Chemistry, University of Yangon, Yangon, 11041, Myanmar.
Bokyoung WooInstitute of Natural Medicine, University of Toyama, 2630-Sugitani, Toyama, 930-0194, Japan.
Sherif Adel ElsabbaghInstitute of Natural Medicine, University of Toyama, 2630-Sugitani, Toyama, 930-0194, Japan.
Qian Qian LiuInstitute of Natural Medicine, University of Toyama, 2630-Sugitani, Toyama, 930-0194, Japan.
Hla NgweDepartment of Chemistry, University of Yangon, Yangon, 11041, Myanmar.
Hiroyuki MoritaInstitute of Natural Medicine, University of Toyama, 2630-Sugitani, Toyama, 930-0194, Japan. hmorita@inm.u-toyama.ac.jp.ORCID http://orcid.org/0000-0001-9963-0587
University of Toyama · JPUniversity of Yangon · MM

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Jatropha multifida is a medicinal plant that belongs to the Euphorbiaceae family. Our investigation revealed that the chloroform extract of J. multifida stems showed anti-melanin deposition activity against α-melanocyte stimulating hormone (α-MSH)- and 3-isobutyl-1-methylxanthine (IBMX)-induced melanogenesis in the mouse melanoma cell line (B16-F10). Further fractionation and purification of the major constituents led to the isolation of two coumarins (1 and 2) and seven known lignoids (3-9). All isolated compounds exhibited anti-melanin deposition activities against the mouse melanoma cell line (B16-F10) with IC

Indexed as

alpha-MSHAnimalsCell Line, TumorDown-RegulationJatrophaMelaninsMelanoma, ExperimentalMiceMonophenol MonooxygenasePlant Extractsalpha-MSHMelaninsMonophenol MonooxygenasePlant ExtractsAnti-melanin depositionJatropha multifidamRNA expressionTyrosinase activityWhitening agent

Identifiers

PMID31055728
OpenAlexW2942804982

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.