Evidence map›Paper›PMID 31055722›Full record

SynthesisDigestive diseases and sciences2019

Machine Learning to Predict Outcomes in Patients with Acute Gastrointestinal Bleeding: A Systematic Review.

Dennis Shung, Michael Simonov, Mark Gentry, Benjamin Au, Loren Laine

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Digestive diseases and sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 8 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 8 syntheses or guidelines pooled it.

  1. Pooled it
  2. Machine Learning for Predicting Stillbirth: A Systematic Review.Reproductive sciences (Thousand Oaks, Calif.) · 2025
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Dennis ShungYale School of Medicine Section of Digestive Diseases, P.O. Box 208019, New Haven, CT, 06520-8019, USA. dennis.shung@yale.edu.ORCID 0000-0001-8226-1842
Michael SimonovYale School of Medicine Section of Digestive Diseases, P.O. Box 208019, New Haven, CT, 06520-8019, USA.
Mark GentryYale School of Medicine Section of Digestive Diseases, P.O. Box 208019, New Haven, CT, 06520-8019, USA.
Benjamin AuYale School of Medicine Section of Digestive Diseases, P.O. Box 208019, New Haven, CT, 06520-8019, USA.
Loren LaineYale School of Medicine Section of Digestive Diseases, P.O. Box 208019, New Haven, CT, 06520-8019, USA.

Funding

TRAINING PROGRAM IN INVESTIGATIVE GASTROENTEROLOGYT32DK007017 · NIDDK · YALE UNIVERSITY · PI Fred Sanford Gorelick, Liza Konnikova · 1986 to 2026
$7.1M
NIDDK NIH HHS T32 DK007017
6 · The paper itself

Abstract

Risk stratification of patients with gastrointestinal bleeding (GIB) is recommended, but current risk assessment tools have variable performance. Machine learning (ML) has promise to improve risk assessment. We performed a systematic review to evaluate studies utilizing ML techniques for GIB. Bibliographic databases and conference abstracts were searched for studies with a population of overt GIB that used an ML algorithm with outcomes of mortality, rebleeding, hemostatic intervention, and/or hospital stay. Two independent reviewers screened titles and abstracts, reviewed full-text studies, and extracted data from included studies. Risk of bias was assessed with an adapted Quality in Prognosis Studies tool. Area under receiver operating characteristic curves (AUCs) were the primary assessment of performance with AUC ≥ 0.80 predefined as an acceptable threshold of good performance. Fourteen studies with 30 assessments of ML models met inclusion criteria. No study had low risk of bias. Median AUC reported in validation datasets for predefined outcomes of mortality, intervention, or rebleeding was 0.84 (range 0.40-0.98). AUCs were higher with artificial neural networks (median 0.93, range 0.78-0.98) than other ML models (0.81, range 0.40-0.92). ML performed better than clinical risk scores (Glasgow-Blatchford, Rockall, Child-Pugh, MELD) for mortality in upper GIB. Limitations include heterogeneity of ML models, inconsistent comparisons of ML models with clinical risk scores, and high risk of bias. ML generally provided good-excellent prognostic performance in patients with GIB, and artificial neural networks tended to outperform other ML models. ML was better than clinical risk scores for mortality in upper GIB.

Indexed as

Decision Support TechniquesHemostatic TechniquesMachine LearningNeural Networks, ComputerAgedClinical Decision-MakingFemaleGastrointestinal HemorrhageHumansMaleMiddle AgedPatient SelectionRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeGastrointestinal bleedingMachine learningRisk assessment

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.