Evidence map›Paper›PMID 31055720›Full record

SynthesisDigestive diseases and sciences2019

Transpancreatic Sphincterotomy Is Effective and Safe in Expert Hands on the Short Term.

Dániel Pécsi, Nelli Farkas, Péter Hegyi, Péter Varjú, Zsolt Szakács, Anna Fábián, Gábor Varga, Zoltán Rakonczay, Emese Réka Bálint, Bálint Erőss and 3 more

Open access · hybridAbstract readComparative StudyMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Digestive diseases and sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Rescue cannulation techniques in difficult biliary access-A comprehensive review.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2025
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Transpancreatic Sphincterotomy: "I Don't Get No Respect".Digestive diseases and sciences · 2021
    Article
  13. Advances in Biliary Access.Current gastroenterology reports · 2020
    Review
  14. Article
  15. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Dániel PécsiInstitute for Translational Medicine, Medical School, University of Pécs, Pecs, Hungary.ORCID 0000-0003-0499-6004
Nelli FarkasInstitute for Translational Medicine, Medical School, University of Pécs, Pecs, Hungary.
Péter HegyiInstitute for Translational Medicine, Medical School, University of Pécs, Pecs, Hungary.
Péter VarjúInstitute for Translational Medicine, Medical School, University of Pécs, Pecs, Hungary.
Zsolt SzakácsInstitute for Translational Medicine, Medical School, University of Pécs, Pecs, Hungary.
Anna FábiánFirst Department of Medicine, University of Szeged, Szeged, Hungary.
Gábor VargaDepartment of Oral Biology, Faculty of Dentistry, Semmelweis University, Budapest, Hungary.
Zoltán RakonczayDepartment of Pathophysiology, University of Szeged, Szeged, Hungary.
Emese Réka BálintDepartment of Pathophysiology, University of Szeged, Szeged, Hungary.
Bálint ErőssInstitute for Translational Medicine, Medical School, University of Pécs, Pecs, Hungary.
József CzimmerDivision of Gastroenterology, First Department of Medicine, Medical School, University of Pécs, Ifjúság u. 13, Pecs, Hungary.
Zoltán SzepesFirst Department of Medicine, University of Szeged, Szeged, Hungary.
Áron VinczeDivision of Gastroenterology, First Department of Medicine, Medical School, University of Pécs, Ifjúság u. 13, Pecs, Hungary. vincze.aron@pte.hu.
University of Pecs · HUUniversity of Szeged · HUSemmelweis University · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In cases of difficult biliary cannulation, transpancreatic sphincterotomy (TPS) can be an alternative approach of biliary access. However, its success and safety profile have not been studied in detail. A systematic review and meta-analysis were performed to study the overall cannulation success and adverse events of TPS. These outcomes were also compared to other advanced cannulation methods. A systematic literature search was conducted to find all relevant articles containing data on TPS. Successful biliary cannulation and complications rates [post-ERCP pancreatitis (PEP), bleeding, and perforation rates] were compared in the pooled analyses of prospective comparative studies. The overall outcomes were calculated involving all studies on TPS. TPS was superior compared to needle-knife precut papillotomy (NKPP) and the double-guidewire method (DGW) regarding cannulation success (odds ratio [OR] 2.32; 95% confidence interval [CI] 1.37-3.93; and OR 2.72; 95% CI 1.30-5.69, respectively). The rate of PEP did not differ between TPS and NKPP or DGW; however, TPS (only retrospective studies were available for comparison) proved to be worse than needle-knife fistulotomy in this regard (OR 4.62; 95% CI 1.36-15.72). Bleeding and perforation rates were similar among these advanced techniques. There were no data about long-term consequences of TPS. The biliary cannulation rate of TPS is higher than that of the other advanced cannulation techniques, while the safety profile is similar to those. However, no long-term follow-up studies are available on the later consequences of TPS; therefore, such studies are strongly needed for its full evaluation.

Indexed as

Ampulla of VaterBiliary TractCatheterizationCholangiopancreatography, Endoscopic RetrogradeClinical CompetenceHumansPancreatic DuctsPancreatitisPostoperative HemorrhageSphincterotomy, EndoscopicTime FactorsCholangiopancreatography, endoscopic retrograde/adverse effectsCholangiopancreatography, endoscopic retrograde/methodsPostoperative hemorrhage/etiologySphincterotomy, endoscopic/adverse effectsSphincterotomy, endoscopic/methods

Identifiers

PMID31055720
PMCPMC6704096
OpenAlexW2944181629

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.