Evidence map›Paper›PMID 31055635›Full record

ArticleArchives of toxicology2019

Minor structural modifications of bisphenol A strongly affect physiological responses of HepG2 cells.

F Padberg, P Tarnow, A Luch, S Zellmer

Open access · hybridAbstract read
PubMed Publisher
In one paragraph

Article in Archives of toxicology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Bisphenols as a Legacy Pollutant, and Their Effects on Organ Vulnerability.International journal of environmental research and public health · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

F PadbergDepartment of Chemical and Product Safety, German Federal Institute for Risk Assessment (BfR), Max-Dohrn Strasse 8-10, 10589, Berlin, Germany. florian.padberg@bfr.bund.de.
P TarnowDepartment of Chemical and Product Safety, German Federal Institute for Risk Assessment (BfR), Max-Dohrn Strasse 8-10, 10589, Berlin, Germany.
A LuchDepartment of Chemical and Product Safety, German Federal Institute for Risk Assessment (BfR), Max-Dohrn Strasse 8-10, 10589, Berlin, Germany.
S ZellmerDepartment of Chemical and Product Safety, German Federal Institute for Risk Assessment (BfR), Max-Dohrn Strasse 8-10, 10589, Berlin, Germany.
Federal Institute for Risk Assessment · DE

Funding

Bundesinstitut für Risikobewertung SFP 1322-655
6 · The paper itself

Abstract

Bisphenols represent a large group of structurally similar compounds. In contrast to bisphenol A (BPA) and bisphenol S (BPS), however, toxicological data are usually scarce, thus making bisphenols an ideal candidate for read-across assessments. BPA, bisphenol C (BPC) and a newly synthesized bisphenol A/C (BPA/C) differ only by one methyl group attached to the phenolic ring. Their EC

Indexed as

Adenosine TriphosphateApoptosisBenzhydryl CompoundsBisphenol A CompoundsCell DivisionCytochromes cEndocrine DisruptorsHep G2 CellsHumansImmunohistochemistryMembrane Potential, MitochondrialMitochondriaPhenolsReceptors, EstrogenStructure-Activity RelationshipTumor Necrosis Factor-alphaAdenosine TriphosphateBenzhydryl Compoundsbisphenol ABisphenol A CompoundsCytochromes cEndocrine DisruptorsPhenolsReceptors, EstrogenTumor Necrosis Factor-alpha2,2-bis(4-hydroxy-3-methylphenyl) propane2,2-bis(4-hydroxyphenyl) propane4,4′-Sulfonyl-diphenolHepG2 cellsIntrinsic apoptosisMitochondria

Identifiers

PMID31055635
OpenAlexW2943303072

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.