ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2019
The endoscopic endonasal approach for pediatric craniopharyngiomas: the key lessons learned.
Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
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Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Fractionated stereotactic radiotherapy in craniopharyngiomas: A systematic review and single arm meta-analysis.Journal of neuro-oncology · 2024Pooled it
- Visual functions in children with craniopharyngioma at diagnosis: A systematic review.PloS one · 2020Pooled it
- Multidisciplinary Management of Pediatric Craniopharyngioma: From Diagnosis to Long-Term Outcomes.Biomedicines · 2026Review
- Contemporary series of transsphenoidal microsurgery in pediatric patients.Neurosurgical review · 2026Article
- Extended endoscopic transtuberculum approach for purely supradiaphragmatic pediatric craniopharyngiomas: outcomes from a single-center cohort study.Neurosurgical review · 2025Article
- Craniopharyngiomas in children: the pendulum moves again for an aggressive surgery-late complications and considerations with a recent series of 26 patients treated in Lyon.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025Article
- CSF leak after pediatric endoscopic endonasal expanded approaches: a series review.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024Article
- A Full View of Papillary Craniopharyngioma Based on Expanded Endonasal Approach: A Comprehensive Clinical Characterization of 101 Cases.Journal of clinical medicine · 2023Article
- Neurosurgical Treatment and Outcome of Pediatric Skull Base Lesions: A Case Series and Review of the Literature.Children (Basel, Switzerland) · 2023Article
- Novel therapeutic approaches for pediatric diencephalic tumors: improving functional outcomes.Frontiers in oncology · 2023Review
- Craniopharyngioma in Pediatrics and Adults.Advances in experimental medicine and biology · 2023Article
- The eagle sign: a new preoperative MRI-based tool for predicting topographic correlation between craniopharyngioma and hypothalamus.Journal of cancer research and clinical oncology · 2022Article
- Extended Neuroendoscopic Endonasal Approach for Resection of Craniopharyngioma in Children.Frontiers in neurology · 2022Article
- Endoscopic extended transsphenoidal surgery for newly diagnosed paediatric craniopharyngiomas.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2021Article
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7 authors.
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Abstract
purposeThe aim of this study is to highlight the role of the endoscopic endonasal approach (EEA) in pediatric craniopharyngiomas by reviewing our experience and the key lessons learned from the application of this approach in children.
methodsBetween 1998 and 2017, 12 pediatric craniopharyngiomas were treated via EEA at our institution. Demographic data, preoperative assessment, tumor features, surgical results, complications, and recurrences were analyzed.
resultsVisual defects were the most frequent presenting sign. Seven craniopharyngiomas were infradiaphragmatic, and five were supradiaphragmatic. The EEA was successfully performed in all cases with no complication related to children's sinonasal anatomy. Gross total resection (GTR) rate was of 75%. Endocrinological disturbances improved in one case (20%) and worsened in three (60%). New onset of diabetes insipidus was observed in four (36%) children. Visual defect improved in 91% of cases, with no new postoperative deficit. Postoperative cerebrospinal fluid (CSF) leak occurred in one patient (8%). Three patients (27%) experienced tumor regrowth, and one craniopharyngioma recurred (mean follow-up, 78 months).
conclusionsThe EEA offers a straight route to the sellar-suprasellar, making it the ideal approach for pediatric infradiaphragmatic craniopharyngiomas. In supradiaphragmatic craniopharyngiomas, the extended EEA provides a clearer and close-up visualization of the tumor-hypothalamus interface, which can grant better results in terms of quality of life. The pediatric skull base anatomy should not represent a contraindication for the endoscopic technique. Larger series encompassing a wider spectrum of pediatric craniopharyngiomas are needed to further support the benefits of this surgical approach.
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