Evidence map›Paper›PMID 31055617›Full record

ArticleEuropean archives of psychiatry and clinical neuroscience2020

Anhedonia in adolescents at ultra-high risk (UHR) of psychosis: findings from a 1-year longitudinal study.

Lorenzo Pelizza, Michele Poletti, Silvia Azzali, Federica Paterlini, Sara Garlassi, Ilaria Scazza, Luigi R Chiri, Simona Pupo, Eva Gebhardt, Andrea Raballo

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Article in European archives of psychiatry and clinical neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 4 pooled it
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 4 syntheses or guidelines pooled it, 41 citations in OpenAlex.

  1. Pooled it
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  3. EPA guidance on assessment of negative symptoms in schizophrenia.European psychiatry : the journal of the Association of European Psychiatrists · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Lorenzo PelizzaDepartment of Mental Health and Pathological Addiction, Azienda USL-IRCCS di Reggio Emilia, Via Amendola n.2, 42100, Reggio Emilia, RE, Italy. lorpelizza@ausl.pr.it.ORCID http://orcid.org/0000-0003-4746-2061
Michele PolettiDepartment of Mental Health and Pathological Addiction, Azienda USL-IRCCS di Reggio Emilia, Via Amendola n.2, 42100, Reggio Emilia, RE, Italy.
Silvia AzzaliDepartment of Mental Health and Pathological Addiction, Azienda USL-IRCCS di Reggio Emilia, Via Amendola n.2, 42100, Reggio Emilia, RE, Italy.
Federica PaterliniDepartment of Mental Health and Pathological Addiction, Azienda USL-IRCCS di Reggio Emilia, Via Amendola n.2, 42100, Reggio Emilia, RE, Italy.
Sara GarlassiDepartment of Mental Health and Pathological Addiction, Azienda USL-IRCCS di Reggio Emilia, Via Amendola n.2, 42100, Reggio Emilia, RE, Italy.
Ilaria ScazzaDepartment of Mental Health and Pathological Addiction, Azienda USL-IRCCS di Reggio Emilia, Via Amendola n.2, 42100, Reggio Emilia, RE, Italy.
Luigi R ChiriDepartment of Primary Care, Azienda USL di Parma, Strada del Quartiere n.2, 43100, Parma, PR, Italy.
Simona PupoAnesthesia and Resuscitation Service, Azienda Ospedaliero-Universitaria di Parma, Via Gramsci n.14, 43100, Parma, PR, Italy.
Eva GebhardtMelograno Medical Psychotherapy Centre, Via Saturnia n.4/a, 00183, Rome, Italy.
Andrea RaballoDivision of Psychiatry, Clinical Psychology and Rehabilitation, Department of Medicine, University of Perugia, Piazza Università n.1, 06123, Perugia, PG, Italy.
Azienda Sanitaria Unità Locale di Reggio Emilia · ITAzienda Unita' Sanitaria Locale di Parma · ITOspedale di Parma · ITUniversity of Perugia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous findings suggested deficits in pleasure experience in schizophrenia, but little is known in psychosis risk prodrome, especially in adolescence. Aim of this study was (1) to assess anhedonia in distinct help-seeking subgroups of adolescents identified through the ultra-high risk (UHR) criteria, (2) to explore any association of anhedonia with other psychopathological aspects in the UHR group, and (3) to monitor longitudinally the stability of anhedonia in UHR individuals across 1-year follow-up period. 123 participants (13-18 years) completed the Comprehensive Assessment of At-Risk Mental States (CAARMS), the Beck Depression Inventory-II, the Schizotypal Personality Questionnaire-Brief version, the Brief-O-LIFE questionnaire (BOL), and the Brief version of the World Health Organization Quality of Life scale (WHOQOL-BREF). Two different indexes of anhedonia were used: CAARMS "Anhedonia" item 4.3 and BOL "Introvertive Anhedonia" subscale scores. No difference in anhedonia levels between UHR and First Episode Psychosis (FEP) groups was found. UHR adolescents showed higher CAARMS and BOL anhedonia scores than non-UHR/FEP. After 1-year follow-up period, UHR adolescents had a significant decrease in severity only in CAARMS anhedonia subscores. In UHR subgroup, CAARMS anhedonia measures showed significant correlations with impaired role functioning and negative symptoms, while BOL anhedonia was significantly correlated with specific schizotypal personality traits concerning interpersonal deficits. Anhedonia is prominent in the psychosis prodrome, also in adolescence. Its severity is not statistically different from that of FEP adolescents and is related to more severe functioning impairment and a worse quality of life.

Indexed as

Prodromal SymptomsAdolescentAnhedoniaDisease SusceptibilityFemaleHumansLongitudinal StudiesMalePsychotic DisordersRiskSchizotypal Personality DisorderSeverity of Illness IndexAnhedoniaDepressionEarly psychosisNegative symptomsUltra-high risk

Identifiers

PMID31055617
OpenAlexW2944387295

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.