Evidence map›Paper›PMID 31054256›Full record

ArticleJournal of Crohn's & colitis2019

Endo-sponge Assisted Early Surgical Closure of Ileal Pouch-anal Anastomotic Leakage Preserves Long-term Function: A Cohort Study.

Karin A Wasmann, Maud A Reijntjes, Merel E Stellingwerf, Cyriel Y Ponsioen, Christianne J Buskens, Roel Hompes, Pieter J Tanis, Willem A Bemelman

Open access · bronzeAbstract read
In one paragraph

Article in Journal of Crohn's & colitis, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Pooled it
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  5. Dehiscence of colorectal anastomosis treated with noninvasive procedures.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2023
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  11. State-of-the-art surgery for ulcerative colitis.Langenbeck's archives of surgery · 2021
    Article
  12. Ileal Pouch-anal Anastomosis Complications and Pouch Failure: A systematic review and meta-analysis.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2021
    Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Karin A WasmannDepartment of Surgery, Amsterdam UMC, Amsterdam, The Netherlands.
Maud A ReijntjesDepartment of Surgery, Amsterdam UMC, Amsterdam, The Netherlands.
Merel E StellingwerfDepartment of Surgery, Amsterdam UMC, Amsterdam, The Netherlands.
Cyriel Y PonsioenDepartment of Gastroenterology and Hepatology, Amsterdam UMC, Amsterdam, The Netherlands.
Christianne J BuskensDepartment of Surgery, Amsterdam UMC, Amsterdam, The Netherlands.
Roel HompesDepartment of Surgery, Amsterdam UMC, Amsterdam, The Netherlands.
Pieter J TanisDepartment of Surgery, Amsterdam UMC, Amsterdam, The Netherlands.
Willem A BemelmanDepartment of Surgery, Amsterdam UMC, Amsterdam, The Netherlands.
Amsterdam University Medical Centers · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsEndo-sponge [Braun Medical] assisted early surgical closure [ESC] is an effective treatment to control pelvic sepsis after ileal pouch-anal anastomosis [IPAA] leakage, and became standard treatment in our centre from 2010 onwards. The aim of this cohort study was to assess the long-term pouch function of ulcerative colitis [UC] patients treated with ESC or conventional management [CM] for anastomotic leakage after IPAA.

methodsConsecutive patients who underwent an IPAA for UC between 2002 and 2017 were included. Patients treated with ESC [2010-2017] or CM [2002-2009] for anastomotic leakage were compared with control patients without anastomotic leakage of the corresponding time period. Main endpoints were long-term pouch function on a 3-point scale and pouch failure, as measured with the validated pouch dysfunction score questionnaire.

resultsSome 280 of 334 patients [84%] returned the pouch dysfunction questionnaire, of whom 18 were treated with ESC and 22 with CM for anastomotic leakage. Control cohorts included 133 [2010-2017] and 107 patients [2002-2009]. Between ESC-treated patients and control patients, pouch function [p = 0.647] and pouch failure rates [0/18 versus 5/133, p >0.99] were similar. CM resulted in worse pouch function [p = 0.016] and a higher pouch failure rate [5/22 versus 5/107, p = 0.013] compared with control patients.

conclusionsESC, in contrast to CM, for IPAA leakage in UC patients is associated with preservation of pouch function and preclusion of pouch failure, probably due to early and effective treatment of pelvic sepsis.

Indexed as

Anastomotic LeakPostoperative ComplicationsProctocolectomy, RestorativeSepsisAdultColitis, UlcerativeColonic PouchesFemaleGelatin Sponge, AbsorbableHumansLong Term Adverse EffectsMaleNetherlandsOutcome and Process Assessment, Health CareRetrospective StudiesWound Closure Techniquesanastomotic leakageIleal pouch-anal anastomosisulcerative colitis

Identifiers

PMID31054256
PMCPMC7006944
OpenAlexW2944158091

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.