Evidence map›Paper›PMID 31054069›Full record

ArticleHuman cell2019

ClC-5 alleviates renal fibrosis in unilateral ureteral obstruction mice.

Shi-Xia Yang, Zheng-Chang Zhang, Hui-Ling Bai

Abstract read
PubMed Publisher
In one paragraph

Article in Human cell, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Shi-Xia YangDepartment of Nephrology, Gansu Provincial Hospital of Traditional Chinese Medicine, No. 418 Guazhou Road, Lanzhou, 730050, Gansu, China. murphy_yeung@126.com.
Zheng-Chang ZhangDepartment of Neurology, Lanzhou University Second Hospital, Lanzhou, 730030, Gansu, China.
Hui-Ling BaiDepartment of Nephrology, Gansu Provincial Hospital of Traditional Chinese Medicine, No. 418 Guazhou Road, Lanzhou, 730050, Gansu, China.
Gansu Provincial Hospital · CNLanzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Renal fibrosis is the major feature of end-stage renal disease with high mortality. Chloride (Cl

Indexed as

Gene ExpressionUp-RegulationAnimalsCadherinsCells, CulturedChloride ChannelsConnective Tissue Growth FactorCytokinesDisease Models, AnimalEpithelial-Mesenchymal TransitionFibrosisInflammation MediatorsKidneyMaleMatrix Metalloproteinase 9Mice, Inbred C57BLCadherinsChloride ChannelsCLC-5 chloride channelConnective Tissue Growth FactorCytokinesInflammation MediatorsMatrix Metalloproteinase 9NF-kappa BPlasminogen Activator Inhibitor 1Transforming Growth Factor beta1ClC-5Epithelial-to-mesenchymal transitionInflammationNF-κB/MMP-9 signalingRenal fibrosis

Identifiers

PMID31054069
OpenAlexW2942927922

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.