Evidence map›Paper›PMID 31054043›Full record

ArticleFish physiology and biochemistry2019

Effects of methylphenidate on the aggressive behavior, serotonin and dopamine levels, and dopamine-related gene transcription in brain of male Nile tilapia (Oreochromis niloticus).

Isabela Gertrudes Batalhão, Daína Lima, Ana Paula Montedor Russi, Camila Nomura Pereira Boscolo, Danilo Grunig Humberto Silva, Thiago Scremin Boscolo Pereira, Afonso Celso Dias Bainy, Eduardo Alves de Almeida

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Fish physiology and biochemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Isabela Gertrudes BatalhãoDepartment of Chemistry and Environmental Sciences, UNESP - Sao Paulo State University, São Paulo, Brazil.
Daína LimaDepartment of Biochemistry, UFSC - Federal University of Santa Catarina, Florianópolis, SP, Brazil.
Ana Paula Montedor RussiDepartment of Physiology, UNESP - Sao Paulo State University, Jaboticabal, São Paulo, SP, Brazil.
Camila Nomura Pereira BoscoloUNIRP - University Center of Rio Preto, São José do Rio Preto, SP, Brazil.
Danilo Grunig Humberto SilvaDepartment of Chemistry and Environmental Sciences, UNESP - Sao Paulo State University, São Paulo, Brazil.
Thiago Scremin Boscolo PereiraUNIRP - University Center of Rio Preto, São José do Rio Preto, SP, Brazil.
Afonso Celso Dias BainyDepartment of Biochemistry, UFSC - Federal University of Santa Catarina, Florianópolis, SP, Brazil.
Eduardo Alves de AlmeidaDepartment of Natural Sciences, FURB Fundação Universidade Regional de Blumenau, Blumenau, SC, Brazil. edualves1976@hotmail.com.ORCID http://orcid.org/0000-0002-4604-9104
Universidade Estadual Paulista (Unesp) · BRUniversidade Federal de Santa Catarina · BRCentro Universitário de Rio Preto · BRFaculdade Ceres · BRUniversidade Regional de Blumenau · BR

Funding

CAPES 001
6 · The paper itself

Abstract

The occurrence of pharmaceuticals in the aquatic environment has increased considerably in the last decades, causing negative biochemical, physiological, and behavioral effects in aquatic organisms. In this study, we evaluated the effects of methylphenidate (MPH) on the aggressive behavior, dopamine-related gene transcript levels, monoamine levels, and carboxylesterase transcript levels and activity in the brain of male Nile tilapia (Oreochromis niloticus). Carboxylesterase activity was also measured in the liver and gills. Fish were exposed for 5 days to MPH at 20 and 100 ng L

Indexed as

AggressionAnimalsBehavior, AnimalBrainCarboxylic Ester HydrolasesCichlidsDopamineDopamine Uptake InhibitorsFish ProteinsGillsLiverMaleMethylphenidateReceptors, DopamineSerotoninTranscription, GeneticCarboxylic Ester HydrolasesDopamineDopamine Uptake InhibitorsFish ProteinsMethylphenidateReceptors, DopamineSerotoninWater Pollutants, ChemicalAggressivenessDopaminergic systemMethylphenidateNile tilapiaSerotonin

Identifiers

PMID31054043
OpenAlexW2943296276

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.