Evidence map›Paper›PMID 31054033›Full record

ArticleBreast cancer research and treatment2019

Elevated serum levels of sialyl Lewis X (sLe

Evan N Cohen, Tamer M Fouad, Bang-Ning Lee, Banu K Arun, Diane Liu, Sanda Tin, Angelica M Gutierrez Barrera, Toshihide Miura, Iwao Kiyokawa, Jun Yamashita and 7 more

Open access · greenAbstract read
In one paragraph

Article in Breast cancer research and treatment, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Adhesion to aggression: unravelling sLeClinical & experimental metastasis · 2025
    Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Sialyl LewisCancers · 2023
    Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Serum-based ComprehensiveIn vivo (Athens, Greece)
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 4 institutions in 3 countries.

Evan N CohenMorgan Welch Inflammatory Breast Cancer Research Program and Clinic, The University of Texas MD Anderson Cancer Center, 1220 Holcombe Blvd, Houston, TX, 77030, USA.ORCID http://orcid.org/0000-0003-4192-9644
Tamer M FouadMorgan Welch Inflammatory Breast Cancer Research Program and Clinic, The University of Texas MD Anderson Cancer Center, 1220 Holcombe Blvd, Houston, TX, 77030, USA.
Bang-Ning LeeMorgan Welch Inflammatory Breast Cancer Research Program and Clinic, The University of Texas MD Anderson Cancer Center, 1220 Holcombe Blvd, Houston, TX, 77030, USA.
Banu K ArunDepartment of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe, Unit 3552, Houston, TX, 77030, USA.
Diane LiuDepartment of Biostatistics, The University of Texas MD Anderson Cancer Center, 1400 Pressler Street, Houston, TX, 77030, USA.
Sanda TinMorgan Welch Inflammatory Breast Cancer Research Program and Clinic, The University of Texas MD Anderson Cancer Center, 1220 Holcombe Blvd, Houston, TX, 77030, USA.
Angelica M Gutierrez BarreraDepartment of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe, Unit 3552, Houston, TX, 77030, USA.
Toshihide MiuraNittobo Medical Co., Ltd., 1, Shiojima Fukuhara, Fukuyama, Koriyama, Fukushima, Japan.
Iwao KiyokawaNittobo Medical Co., Ltd., 1, Shiojima Fukuhara, Fukuyama, Koriyama, Fukushima, Japan.
Jun YamashitaNittobo Medical Co., Ltd., 1, Shiojima Fukuhara, Fukuyama, Koriyama, Fukushima, Japan.
Ricardo H AlvarezMorgan Welch Inflammatory Breast Cancer Research Program and Clinic, The University of Texas MD Anderson Cancer Center, 1220 Holcombe Blvd, Houston, TX, 77030, USA.
Vicente ValeroDepartment of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe, Unit 3552, Houston, TX, 77030, USA.
Wendy A WoodwardMorgan Welch Inflammatory Breast Cancer Research Program and Clinic, The University of Texas MD Anderson Cancer Center, 1220 Holcombe Blvd, Houston, TX, 77030, USA.
Yu ShenDepartment of Biostatistics, The University of Texas MD Anderson Cancer Center, 1400 Pressler Street, Houston, TX, 77030, USA.
Naoto T UenoMorgan Welch Inflammatory Breast Cancer Research Program and Clinic, The University of Texas MD Anderson Cancer Center, 1220 Holcombe Blvd, Houston, TX, 77030, USA.
Massimo CristofanilliMorgan Welch Inflammatory Breast Cancer Research Program and Clinic, The University of Texas MD Anderson Cancer Center, 1220 Holcombe Blvd, Houston, TX, 77030, USA.
James M ReubenMorgan Welch Inflammatory Breast Cancer Research Program and Clinic, The University of Texas MD Anderson Cancer Center, 1220 Holcombe Blvd, Houston, TX, 77030, USA. jreuben@mdanderson.org.
The University of Texas MD Anderson Cancer Center · USNitto Chemical Industry (Japan) · JPMichael E. DeBakey VA Medical Center · USNorthwestern University · US

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Fabien Delerue · 1985 to 2026
$290.8M
Human Breast Cancer Stem Cell SurrogatesR01CA138239 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI CRISTOFANILLI, MASSIMO, REUBEN, JAMES MARTIN · 2008 to 2012
$2.8M
NCI NIH HHS P30 CA016672NCI NIH HHS R01 CA138239
6 · The paper itself

Abstract

purposeThe carbohydrate sialyl Lewis

methodsWe retrospectively measured sLe

resultsMedian serum sLe

conclusionElevated serum sLe

Indexed as

BiomarkersBiomarkers, TumorBreast NeoplasmsCase-Control StudiesCluster AnalysisCytokinesFemaleHumansInflammation MediatorsNeoplasm StagingPrognosisProportional Hazards ModelsRetrospective StudiesSialyl Lewis X AntigenSurvival AnalysisBiomarkersBiomarkers, TumorCytokinesInflammation MediatorsSialyl Lewis X AntigenBreast cancerInflammatory cytokinesSerumSialyl Lewisx (SLEX)

Identifiers

PMID31054033
PMCPMC6653624
OpenAlexW2943303660

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.