Evidence map›Paper›PMID 31054005›Full record

ReviewJournal of muscle research and cell motility2020

Actin-tropomyosin distribution in non-muscle cells.

Dietmar J Manstein, J C M Meiring, E C Hardeman, Peter W Gunning

Open access · hybridAbstract readReview
In one paragraph

Review in Journal of muscle research and cell motility, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. ALPK2 prevents cardiac diastolic dysfunction in heart failure with preserved ejection fraction.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Dietmar J MansteinInstitute for Biophysical Chemistry, OE4350, Medizinische Hochschule Hannover, 30625, Hannover, Germany. manstein.dietmar@mh-hannover.de.ORCID 0000-0003-0763-0147
J C M MeiringCellular and Genetic Medicine Unit, School of Medical Sciences, University of New South Wales, Sydney, NSW, 2052, Australia.
E C HardemanCellular and Genetic Medicine Unit, School of Medical Sciences, University of New South Wales, Sydney, NSW, 2052, Australia.
Peter W GunningCellular and Genetic Medicine Unit, School of Medical Sciences, University of New South Wales, Sydney, NSW, 2052, Australia. p.gunning@unsw.edu.au.
UNSW Sydney · AUMedizinische Hochschule Hannover · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The interactions of cytoskeletal actin filaments with myosin family motors are essential for the integrity and function of eukaryotic cells. They support a wide range of force-dependent functions. These include mechano-transduction, directed transcellular transport processes, barrier functions, cytokinesis, and cell migration. Despite the indispensable role of tropomyosins in the generation and maintenance of discrete actomyosin-based structures, the contribution of individual cytoskeletal tropomyosin isoforms to the structural and functional diversification of the actin cytoskeleton remains a work in progress. Here, we review processes that contribute to the dynamic sorting and targeted distribution of tropomyosin isoforms in the formation of discrete actomyosin-based structures in animal cells and their effects on actin-based motility and contractility.

Indexed as

ActinsHumansTropomyosinActinsTropomyosinActinActin binding proteinCytoplasmic protein sortingCytoskeletonMyosinTropomyosin

Identifiers

PMID31054005
PMCPMC7109190
OpenAlexW2942655277

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.