Evidence map›Paper›PMID 31053988›Full record

ReviewPlant molecular biology2019

Overexpression of PsnSuSy1, 2 genes enhances secondary cell wall thickening, vegetative growth, and mechanical strength in transgenic tobacco.

Meilang Li, Shuan Wang, Yingying Liu, Yang Zhang, Menxuan Ren, Lulu Liu, Tingting Lu, Hairong Wei, Zhigang Wei

RetractedAbstract readReviewRetracted Publication
PubMed Publisher
In one paragraph

Review in Plant molecular biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
7.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. The sucrose synthase gene family in blueberry (Frontiers in plant science · 2025
    Article
  4. Cell wall regulation by carbon allocation and sugar signaling.Cell surface (Amsterdam, Netherlands) · 2023
    Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Meilang LiState Key Laboratory of Tree Genetics and Breeding, Northeast Forestry University, Harbin, 150040, Heilongjiang, People's Republic of China.
Shuan WangState Key Laboratory of Tree Genetics and Breeding, Northeast Forestry University, Harbin, 150040, Heilongjiang, People's Republic of China.
Yingying LiuState Key Laboratory of Tree Genetics and Breeding, Northeast Forestry University, Harbin, 150040, Heilongjiang, People's Republic of China.
Yang ZhangState Key Laboratory of Tree Genetics and Breeding, Northeast Forestry University, Harbin, 150040, Heilongjiang, People's Republic of China.
Menxuan RenState Key Laboratory of Tree Genetics and Breeding, Northeast Forestry University, Harbin, 150040, Heilongjiang, People's Republic of China.
Lulu LiuState Key Laboratory of Tree Genetics and Breeding, Northeast Forestry University, Harbin, 150040, Heilongjiang, People's Republic of China.
Tingting LuState Key Laboratory of Tree Genetics and Breeding, Northeast Forestry University, Harbin, 150040, Heilongjiang, People's Republic of China.
Hairong WeiSchool of Forest Resource and Environmental Science, Michigan Technological University, Houghton, MI, 49931, USA.
Zhigang WeiState Key Laboratory of Tree Genetics and Breeding, Northeast Forestry University, Harbin, 150040, Heilongjiang, People's Republic of China. zhigangwei1973@163.com.ORCID http://orcid.org/0000-0002-0777-9817
Northeast Forestry University · CNMichigan Technological University · US

Funding

Foundation Research Fund for the Central Universities of China 2572016EAJ2National Nature Science Fund 31770640Returned Overseas Researcher Fund of Heilongjiang Province LC2015012the 111 Project B16010
6 · The paper itself

Abstract

key messageTwo homologs PsnSuSy1 and PsnSuSy2 from poplar played largely similar but little distinct roles in modulating sink strength, accelerating vegetative growth and modifying secondary growth of plant. Co-overexpression of them together resulted in small but perceptible additive effects. Sucrose synthase (SuSy) acts as a crucial determinant of sink strength by controlling the conversion of sucrose into UDP-glucose, which is not only the sole precursor for cellulose biosynthesis but also an extracellular signaling molecule for plants growth. Therefore, modification of SuSy activity in plants is of utmost importance. We have isolated two SuSy genes from poplar, PsnSuSy1 and PsnSuSy2, which were preferentially expressed in secondary xylem/phloem. To investigate their functions, T2 tobacco transgenic lines of PsnSuSy1 and PsnSuSy2 were generated and then crossed to generate PsnSuSy1/PsnSuSy2 dual overexpression transgenic lines. SuSy activities in all lines were significantly increased though PsnSuSy1/PsnSuSy2 lines only exhibited slightly higher SuSy activities than either PsnSuSy1 or PsnSuSy2 lines. The significantly increased fructose and glucose, engendered by augmented SuSy activities, caused the alternations of many physiological, biochemical measures and phenotypic traits that include accelerated vegetative growth, thickened secondary cell wall, and increased stem breaking force, accompanied with altered expression levels of related pathway genes. The correlation relationships between SuSy activities and many of these traits were statistically significant. However, differences of almost all traits among three types of transgenic lines were insignificant. These findings clearly demonstrated that PsnSuSy1 and PsnSuSy2 had similar but little distinct functions and insubstantial additive effects on modulating sink strength and affecting allocation of carbon elements among secondary cell wall components.

Indexed as

Gene Expression Regulation, PlantCelluloseCell WallChlorophyllCloning, MolecularGene Expression ProfilingGenes, PlantGlucosyltransferasesLigninNicotianaPhloemPhotosynthesisPlant ProteinsPlants, Genetically ModifiedPolysaccharidesPopulusCelluloseChlorophyllGlucosyltransferaseshemicelluloseLigninPlant ProteinsPolysaccharidesSucrosesucrose synthaseAdditive effectFibre formationOverexpressionPsnSuSy1PsnSuSy2Secondary cell wallVegetative growth

Identifiers

PMID31053988
OpenAlexW2944268818

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.