ArticleWorld journal of microbiology & biotechnology2019
Isolation of taxol producing endophytic fungus Alternaria brassicicola from non-Taxus medicinal plant Terminalia arjuna.
Article in World journal of microbiology & biotechnology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 48 citations in OpenAlex.
- Acetylcholinesterase inhibiting withanolides from Curvularia pseudobrachyspora, an endophytic fungus of Withania somnifera (L.) Dunal.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026Article
- Inspired by taxol: biosynthesis and engineering of hypericin and other phytochemicals in Hypericum.Planta · 2026Review
- Community Structure Diversity of Endophytic Fungi inJournal of fungi (Basel, Switzerland) · 2025Article
- Response of Endophytic Microbial Communities and Quality ofMicroorganisms · 2025Article
- Comprehensive strategies for paclitaxel production: insights from plant cell culture, endophytic microorganisms, and synthetic biology.Horticulture research · 2025Article
- Pharmacological properties of biomimetic synthesized silver nanoparticles from endophytic fungus Coniothyrium chaingmaiense: KUMBMDBT-25.Scientific reports · 2025Article
- Chemical characterization, pathway enrichments and bioactive potentials of catechin-producing endophytic fungi isolated from tea leaves.RSC advances · 2024Article
- Paclitaxel production from endophytic3 Biotech · 2024Article
- Paclitaxel - a Product of Fungal Secondary Metabolism or an Artefact?Planta medica · 2024Review
- Paclitaxel and its semi-synthetic derivatives: comprehensive insights into chemical structure, mechanisms of action, and anticancer properties.European journal of medical research · 2024Review
- Way to efficient microbial paclitaxel mass production.Synthetic and systems biotechnology · 2023Review
- Cultivable Endophyte Resources in Medicinal Plants and Effects on Hosts.Life (Basel, Switzerland) · 2023Review
- Eco-friendly synthesized silver nanoparticles from endophytic fungus Phyllosticta owaniana: KUMBMDBT-32 and evaluation of biomedical properties.Archives of microbiology · 2023Article
- Article
- Metabolites extracted from microorganisms as potential inhibitors of glycosidases (α-glucosidase and α-amylase): A review.Frontiers in microbiology · 2022Review
- A Compressive Review about TaxolMolecules (Basel, Switzerland) · 2020Review
- Untapped Potentials of Endophytic Fungi: A Review of Novel Bioactive Compounds with Biological Applications.Microorganisms · 2020Review
- Diversity and Antimicrobial Activity of Endophytic Fungi Isolated fromInternational journal of molecular sciences · 2020Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the present study, an endophytic fungal strain was isolated from its non-Taxus host plant Terminalia arjuna and identified as Alternaria brassicicola based on its morphological characteristics and internal transcribed spacer sequence analysis. This fungus was grown in potato dextrose broth and analyzed for the presence of taxol by using chromatographic and spectrometric techniques. The ethyl acetate extract of A.brassicicola was subjected to column chromatography. Among the different fractions, the fraction 7 showed positive to taxol, which was further confirmed by UV absorption, HPLC, FTIR spectra and LC-ESI-MS by comparing with the authentic taxol (Paclitaxel). The peaks of fraction 7 obtained by UV spectroscopy, FTIR and HPLC analysis were quite similar to that of standard taxol confirming the presence of taxol. A parent ion peak of m/z 854.95 was observed in the LC-ESI-MS spectrum which was similar to paclitaxel with reported m/z of 854 [M+H]
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