ArticleClinical research in cardiology : official journal of the German Cardiac Society2020
Right atrial-right ventricular coupling in heart failure with preserved ejection fraction.
Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 15 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Comparison of Non-invasive Assessment of Cardiac Fibrosis by MRI Derived T1-Mapping and Ventricular Intrinsic Diastolic Function by Pressure-volume-analysis in Patients With Heart Failure With Preserved Ejection Fraction
Afterload Dependence of Right Ventricular Myocardial Remodeling and Intrinsic Right Ventricular Myocardial Function in Heart Failure With Preserved Ejection Fraction
Who cites it
15 citing papers in PubMed, 31 citations in OpenAlex.
- Prognostic Relevance of Speckle Tracking-Derived Biatrial Stiffness Index in Patients with Dilated Cardiomyopathy.Journal of clinical medicine · 2026Article
- Clinical Utility of Atrioventricular Coupling Index in Cardiovascular Disease.Journal of the American Heart Association · 2025Review
- Comparison of right atrial volume measurements using single-plane area-length and stack-of-short-axis methods: A 3.0 T cardiac magnetic resonance study.BMC medical imaging · 2025Article
- Running on empty: Factors underpinning impaired cardiac output reserve in heart failure with preserved ejection fraction.Experimental physiology · 2025Review
- Hemodynamic interplay of ventricular, atrial and aortic function in patients after arterial switch operation: insights from cardiac MRI.Cardiovascular diagnosis and therapy · 2025Article
- Right Atrial Phasic Function in Heart Failure with Preserved Ejection Fraction: Cardiac Magnetic Resonance Feature Tracking and Outcomes.Journal of clinical medicine · 2023Article
- Evaluation of right atrial function by two-dimensional echocardiography and strain imaging in patients with RCA CTO recanalization.BMC cardiovascular disorders · 2023Article
- Cardio-Vascular Interaction Evaluated by Speckle-Tracking Echocardiography and Cardio-Ankle Vascular Index in Hypertensive Patients.International journal of molecular sciences · 2022Observational
- Changes in left atrial function in patients undergoing cardioversion for atrial fibrillation: relevance of left atrial strain in heart failure.Clinical research in cardiology : official journal of the German Cardiac Society · 2022Article
- Right Ventricular and Right Atrial Function Are Less Compromised in Pulmonary Hypertension Secondary to Heart Failure With Preserved Ejection Fraction: A Comparison With Pulmonary Arterial Hypertension With Similar Pressure Overload.Circulation. Heart failure · 2022Article
- Cardiovascular magnetic resonance for the diagnosis and management of heart failure with preserved ejection fraction.Heart failure reviews · 2022Review
- Invasive Right Ventricular Pressure-Volume Analysis: Basic Principles, Clinical Applications, and Practical Recommendations.Circulation. Heart failure · 2022Article
- Cardiovascular magnetic resonance feature tracking for characterization of patients with heart failure with preserved ejection fraction: correlation of global longitudinal strain with invasive diastolic functional indices.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2020Article
- Impact of Right Atrial Physiology on Heart Failure and Adverse Events after Myocardial Infarction.Journal of clinical medicine · 2020Article
- Evaluation of diastolic function in hypertrophic cardiomyopathy and cardiac amyloidosis through semi-automatic assessment - a multi-center, multi-vendor cardiovascular magnetic resonance study.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic ResonanceArticle
Corrections and comments
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Authors and funding
13 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRight ventricular (RV) function is prognostically relevant in heart failure with preserved ejection fraction (HFpEF) but data on profound assessment of RV and right atrial (RA) interaction in HFpEF are lacking. The current study characterizes RV and RA interaction using invasive pressure-volume-loop analysis and cardiac magnetic resonance imaging (CMR) data. METHODS AND
resultsWe performed CMR and myocardial feature-tracking in 24 HFpEF patients and 12 patients without HFpEF. Invasive pressure-volume-loops were obtained to evaluate systolic and diastolic RV properties. RV early filling was determined from CMR RV volume-time curves. RV systolic function was slightly increased in HFpEF (RV EF 68 ± 8 vs. 60 ± 9%, p = 0.01), while no differences in RV stroke volume were found (45 ± 7 vs 42 ± 9 ml/m
conclusionIn compensated HFpEF patients RV early filling was impaired and compensated by increased RA booster pump function, while RV systolic function was preserved. Impaired RV diastology and RA-RV interaction were linked to impaired exercise tolerance and RA-RV-coupling seems to be independent of RV relaxation, suggestive of an independent pathophysiological contribution of RA dysfunction in HFpEF. CLINICAL-TRIAL-REGISTRATION: NCT02459626 (www.clinicaltrials.gov).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.