Evidence map›Paper›PMID 31053877›Full record

Observational studyClinical neuroradiology2020

Intracranial Artery Injury in HIV-negative Tuberculous Meningitis : A High-Resolution Vessel Wall Imaging Study.

Tingting Lu, Yan Zou, Ting Jiang, Yu Yang, Aimin Wu, Hongbing Chen, Zhuang Kang, Xinqing Lin, Yimin Fang, Zhengqi Lu

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Clinical neuroradiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Tingting LuDepartment of Neurology, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Yan ZouDepartment of Radiology, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Ting JiangDepartment of Radiology, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Yu YangDepartment of Neurology, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Aimin WuDepartment of Neurology, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Hongbing ChenDepartment of Neurology and Stroke Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Zhuang KangDepartment of Radiology, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Xinqing LinState Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Disease, First Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.
Yimin FangGuangzhou Chest Hospital, Guangzhou, China. fangyimin2006@163.com.
Zhengqi LuDepartment of Neurology, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China. lzq1828@aliyun.com.
Sun Yat-sen University · CNThird Affiliated Hospital of Sun Yat-sen University · CNGuangzhou Chest Hospital · CNState Key Laboratory of Respiratory Disease · CNThe First Affiliated Hospital, Sun Yat-sen University · CN

Funding

Medical Scientific Research Foundation of Guangdong Province A2016224National Natural Science Foundation of China 81701172Special Fund Project of Science and Technology in Guangdong Province 2017B020247038
6 · The paper itself

Abstract

purposeThe features of intracranial arterial injury in tuberculous meningitis (TBM) are of important diagnostic and prognostic value. The study aimed to elucidate the high-resolution vessel wall imaging (HR-VWI) manifestations of intracranial arterial insults in TBM.

methodsThe clinical data, routine cranial magnetic resonance imaging, magnetic resonance angiography (MRA) and HR-VWI before and after contrast enhancement of intracranial arteries in clinically diagnosed TBM patients were retrospectively analyzed.

resultsIn this study 27 TBM patients were included. Abnormalities in the intracranial arteries were detected in all patients using HR-VWI. Typical vessel insults included nodular or granular lesions, related thickness and prominent enhancement in the wall, and lumen narrowing or occlusion. The most frequently involved arteries were the C4 segment of the internal carotid artery and the P1 segment of the posterior cerebral artery. The lesions were consistent with disease stage and disease duration and correlated with infarction.

conclusionThe use of HR-VWI revealed that cerebral artery involvement in patients with TBM is much more common and extensive than in previous radiological reports. The use of HR-VWI improves recognition of arterial pathologies and has diagnostic value in patients with TBM.

Indexed as

AdultCerebral ArteriesContrast MediaFemaleHumansImage EnhancementIntracranial Arterial DiseasesMagnetic Resonance AngiographyMagnetic Resonance ImagingMaleRetrospective StudiesTuberculosis, MeningealContrast MediaHigh-resolution vessel wall imagingInternal carotid arteryMagnetic resonance angiographyMiddle cerebral arteryTuberculous meningitis

Identifiers

PMID31053877
OpenAlexW2942823361

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.