ArticleScientific reports2019
High spatial resolution scintillator dosimetry of synchrotron microbeams.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Megavoltage photon minibeam production through the embedded multi-leaf collimator of a clinical linac: A dosimetric characterization.Medical physics · 2026Article
- Volumetric FLASH dosimetryPhysics in medicine and biology · 2026Article
- Time-resolved point dosimetry for spread-out Bragg-peak proton FLASH using fibre-coupled scintillators.Medical physics · 2026Article
- The Potential of Dosimetry and the Visualization of Microbeam Arrays in NIPAM Gel at the PETRA III Synchrotron.Gels (Basel, Switzerland) · 2025Article
- Playing Hard with Si: Challenges and Opportunities for New Materials in Radiation Therapy Dosimetry.Advanced materials (Deerfield Beach, Fla.) · 2025Review
- Application of Synchrotron Radiation in Fundamental Research and Clinical Medicine.Biomedicines · 2025Review
- Microstrip plastic scintillating detector system for quality assurance in synchrotron microbeam radiotherapy.Scientific reports · 2025Article
- Grid/lattice therapy: consideration of small field dosimetry.The British journal of radiology · 2024Review
- Ultra-high dose rate electron beams and the FLASH effect: From preclinical evidence to a new radiotherapy paradigm.Medical physics · 2022Review
- Megavolt bremsstrahlung measurements from linear induction accelerators demonstrate possible use as a FLASH radiotherapy source to reduce acute toxicity.Scientific reports · 2021Article
- A microfluidic dosimetry cell to irradiate solutions with poorly penetrating radiations: a step towards online dosimetry for synchrotron beamlines.Journal of synchrotron radiation · 2021Article
- Evaluation of a pixelated large format CMOS sensor for x-ray microbeam radiotherapy.Medical physics · 2020Article
- Investigating the Dosimetric Characteristics of Microbeam Radiation Treatment.Journal of medical signals and sensorsArticle
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Microbeam radiation therapy is a novel pre-clinical external beam therapy that uses high-brilliance synchrotron X-rays to deliver the necessary high dose rates. The unique conditions of high dose rate and high spatial fractionation demand a new class of detector to experimentally measure important beam quality parameters. Here we demonstrate the highest spatial resolution plastic scintillator fibre-optic dosimeter found in the literature to date and tested it on the Imaging and Medical Beam-Line at the Australian Synchrotron in a X-ray beam where the irradiation dose rate was 4435 Gy/s. With a one-dimensional spatial resolution of 10 μm the detector is able to resolve the individual microbeams (53.7 ± 0.4 μm wide), and measure the peak-to-valley dose ratio to be 55 ± 17. We also investigate the role of radioluminescence in the optical fibre used to transport the scintillation photons, and conclude that it creates a significant contribution to the total light detected.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.