Evidence map›Paper›PMID 31053691›Full record

ArticleIET nanobiotechnology2019

Synthesis, characterisation and anti-tumour activity of biopolymer based platinum nanoparticles and 5-fluorouracil loaded platinum nanoparticles.

Deepika Godugu, Sashidhar Rao Beedu

Abstract read
In one paragraph

Article in IET nanobiotechnology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Deepika GoduguDepartment of Biochemistry, University College of Science, Osmania University, Hyderabad-500 007, Telangana, India.
Sashidhar Rao BeeduDepartment of Biochemistry, University College of Science, Osmania University, Hyderabad-500 007, Telangana, India. sashi_rao@yahoo.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A facile and green synthesis of platinum nanoparticles [gum kondagogu platinum nanoparticles (GKPtNP)] using biopolymer- gum kondagogu was developed. The formation of GKPtNP was confirmed by ultraviolet (UV)-visible spectroscopy, scanning electron microscopy-energy dispersive X-ray spectroscopy, transmission electron microscopy, X-ray diffraction, Zeta potential, Fourier transform infrared, inductively coupled plasma mass spectroscopy. The formed GKPtNP are well dispersed, homogeneous with a size of 2-4 ± 0.50 nm, having a negative zeta potential (-46.1 mV) indicating good stability. 5-Fluorouracil (5FU) was loaded onto the synthesised GKPtNP, which leads to the development of a new combination of nanomedicine (5FU-GKPtNP). The in vitro drug release studies of 5FU-GKPtNP in pH 7.4 showed a sustained release profile over a period of 120 min.

Indexed as

Antineoplastic AgentsBiological AssayBiopolymersDrug CarriersFluorouracilMetal NanoparticlesPlatinumAntineoplastic AgentsBiopolymersDrug CarriersFluorouracilPlatinum

Identifiers

PMID31053691
PMCPMC8676425

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.