ArticleClinical therapeutics2019
When the Female Heart Stops: Sex and Gender Differences in Out-of-Hospital Cardiac Arrest Epidemiology and Resuscitation.
Article in Clinical therapeutics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 38 citations in OpenAlex.
- The implementation of diverse skin-toned female manikins in hospital provider basic life support training.Resuscitation plus · 2026Article
- The impact of additional special emergency medical service units on non-traumatic adult out-of-hospital cardiac arrest outcomes in a high-resource metropolitan area.Resuscitation plus · 2025Article
- Sex Differences in In-Hospital Mortality Among Patients Receiving Veno-Arterial Extracorporeal Membrane Oxygenation and Extracorporeal Cardiopulmonary Resuscitation: A Propensity Score-Matched Analysis.Journal of the American Heart Association · 2025Article
- Sex differences in out-of-hospital cardiac arrest.European heart journal open · 2025Article
- Gender disparities in out-of-hospital cardiac arrest: implications for public health and bystander interventions in Zhengzhou.Frontiers in medicine · 2025Article
- Sex Differences in Advanced Therapeutic Interventions for Intermediate- and High-Risk Pulmonary Embolism.Clinical therapeutics · 2024Article
- The Interaction Effect of Age, Initial Rhythm, and Location on Outcomes After Out-of-Hospital Cardiac Arrest: A Retrospective Cohort Study.Journal of clinical medicine · 2024Article
- Epidemiology and outcome of out-of-hospital cardiac arrest in Salt Lake City: Sex-based investigations.Journal of the American College of Emergency Physicians open · 2024Article
- Analgesia Administration by Sex Among Pediatric Emergency Department Patients with Abdominal Pain.JEM reports · 2024Article
- Review
- Prediction Models for Return of Spontaneous Circulation in Patients with Cardiac Arrest: A Systematic Review and Critical Appraisal.Emergency medicine international · 2023Review
- Sex and out-of-hospital cardiac arrest survival: a systematic review.Annals of intensive care · 2022Review
- Sex and Gender Equity in Prehospital Electrocardiogram Acquisition.Prehospital and disaster medicine · 2022Article
- Sex difference in circulating PCSK9 and its clinical implications.Frontiers in pharmacology · 2022Review
- Mortality after cardiopulmonary resuscitation on a medical ICU : A sex-specific outcome analysis.Wiener klinische Wochenschrift · 2021Article
- Factors associated with return of spontaneous circulation after out-of-hospital cardiac arrest in Poland: a one-year retrospective study.BMC cardiovascular disorders · 2020Article
- Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 1 country.
Funding
Abstract
Sex- and gender-based differences are emerging as clinically significant in the epidemiology and resuscitation of patients with out-of-hospital cardiac arrest (OHCA). Female patients tend to be older, experience arrest in private locations, and have fewer initial shockable rhythms (ventricular fibrillation/ventricular tachycardia). Despite standardized algorithms for the management of OHCA, women are less likely to receive evidence-based interventions, including advanced cardiac life support medications, percutaneous coronary intervention, and targeted temperature management. While some data suggest a protective mechanism of estrogen in the heart, brain, and kidney, its role is incompletely understood. Female patients experience higher mortality from OHCA, prompting the need for sex-specific research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.