Evidence map›Paper›PMID 31053215›Full record

Trial reportJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2019

Randomized Controlled Trial of Imagery Rehearsal for Posttraumatic Nightmares in Combat Veterans.

Gerlinde C Harb, Joan M Cook, Andrea J Phelps, Philip R Gehrman, David Forbes, Russell Localio, Ilan Harpaz-Rotem, Ruben C Gur, Richard J Ross

Registry-linked trialOpen access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00691626 (CBT for Nightmares in OEF/OIF Veterans), which is not on this map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
12.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00691626 nacompletednot on this map

CBT for Nightmares in OEF/OIF Veterans

TypeinterventionalSponsorVA Office of Research and DevelopmentRan2009 to 2019Enrolled108ConditionsPosttraumatic Stress Disorder, Sleep Disorders, NightmaresArmsCBT for Insomnia plus Imagery Rehearsal, CBT for Insomnia plus psychoeducation
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 69 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Cognitive behavioral therapy for insomnia treatment attrition in patients with weekly nightmares.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2023
    Trial
  5. Brief behavioral treatment for insomnia decreases trauma-related nightmare frequency in veterans.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022
    Trial
  6. Trial
  7. A pilot randomized controlled trial of cognitive behavioral treatment for trauma-related nightmares in active duty military personnel.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2020
    Trial
  8. Efficacy of imagery rehearsal therapy in the treatment of traumatic nightmares in youth with complex post-traumatic stress disorder.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2026
    Review
  9. Targeted dream incubation and dream self-efficacy.Sleep advances : a journal of the Sleep Research Society · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Review
  16. Review
  17. Article
  18. Treatment of Sleep Comorbidities in Posttraumatic Stress Disorder.Current treatment options in psychiatry · 2020
    Article
  19. Sleep in PTSD: treatment approaches and outcomes.Current opinion in psychology · 2020
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Gerlinde C HarbCorporal Michael J. Crescenz VA Medical Center, Philadelphia, Pennsylvania.
Joan M CookYale University and National Center for PTSD, New Haven, Connecticut.
Andrea J PhelpsPhoenix Australia Centre for Posttraumatic Mental Health, Melbourne, Australia.
Philip R GehrmanCorporal Michael J. Crescenz VA Medical Center, Philadelphia, Pennsylvania.
David ForbesPhoenix Australia Centre for Posttraumatic Mental Health, Melbourne, Australia.
Russell LocalioUniversity of Pennsylvania, Perelman School of Medicine, Philadelphia, Pennsylvania.
Ilan Harpaz-RotemYale University and National Center for PTSD, New Haven, Connecticut.
Ruben C GurUniversity of Pennsylvania, Perelman School of Medicine, Philadelphia, Pennsylvania.
Richard J RossCorporal Michael J. Crescenz VA Medical Center, Philadelphia, Pennsylvania.
Philadelphia VA Medical Center · USMental Health Australia · AUUniversity of Pennsylvania · USYale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

STUDY

objectivesTo examine the efficacy of imagery rehearsal (IR) combined with cognitive behavioral therapy for insomnia (CBT-I) compared to CBT-I alone for treating recurrent nightmares in military veterans with posttraumatic stress disorder (PTSD).

methodsIn this randomized controlled study, 108 male and female United States veterans of the Iraq and Afghanistan conflicts with current, severe PTSD and recurrent, deployment-related nightmares were randomized to six sessions of IR + CBT-I (n = 55) or CBT-I (n = 53). Primary outcomes were measured with the Nightmare Frequency Questionnaire (NFQ) and Nightmare Distress Questionnaire (NDQ).

resultsImprovement with treatment was significant (29% with reduction in nightmare frequency and 22% with remission). Overall, IR + CBT-I was not superior to CBT-I (NFQ: -0.12; 95% confidence interval = -0.87 to 0.63; likelihood ratio chi square = 4.7(3),

conclusionsCombining IR with CBT-I conferred no advantage overall. Further research is essential to examine the possibly greater benefit of adding IR to CBT-I for some subgroups of veterans with PTSD. CLINICAL

trial registrationRegistry: ClinicalTrials.gov; Title: Cognitive Behavioral Therapy (CBT) for Nightmares in Operation Enduring Freedom/Operation Iraqi Freedom (OEF/OIF) Veterans; Identifier: NCT00691626; URL: https://clinicaltrials.gov/ct2/show/NCT00691626.

Indexed as

AdultAfghan Campaign 2001-Cognitive Behavioral TherapyDreamsFemaleHumansImagery, PsychotherapyIraq War, 2003-2011MaleStress Disorders, Post-TraumaticTreatment OutcomeUnited StatesVeteranscognitive behavioral therapyinsomnianightmaresposttraumatic stress disorder

Identifiers

PMID31053215
PMCPMC6510682
OpenAlexW2946280739

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.